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Montelucaste diminui as crises convulsivas em animais abrasados e potencializa o efeito anticonvulsivante do fenobarbital
(Universidade Federal de Santa Maria, 2015-07-28)
Epilepsy is a chronic neurological disease characterized by recurrent, unprovoked seizures. Evidence suggests that inflammation plays a role in the pathophysiology of seizures. Although cysteinyl leukotrienes (CysLTs) have ...
Modulação gênica dos receptores de prostaglandina E2 em células miometriais e cervicais em partos induzidos com prostaglandinas: estudo in vivo e in vitro
(Universidade Federal de Santa Maria, 2015-09-18)
The mechanisms involved in human parturition, and the molecular changes that occur during the transition from pregnancy and birth are not completely elucidated. Endogenous or administered prostaglandins, including the PGE1 ...
Potencial terapêutico do extrato metanólico de Condalia buxifolia reissek no controle da dor aguda: estudo do mecanismo de ação
(Universidade Federal de Santa Maria, 2015-08-06)
The medicinal plant Condalia buxifolia has been traditionally used to treat inflammatory processes. The present study aimed to evaluate the phytochemical profile and the analgesic effect of the methanolic extract from the ...
Mecanismos bioquímicos e moleculares envolvidos em efeitos comportamentais induzidos por reserpina em ratos e C. elegans com ênfase em parâmetros oxidativos e dopaminérgicos
(Universidade Federal de Santa Maria, 2015-01-16)
Animal models as reserpine are helpful to understand the pathophysiology of several diseases with involuntary movements, as Parkinson s disease (PD), and to search efficient treatments. The present study tested the effects ...
Papel da Na+, K+ - ATPase no modelo de epilepsia do lobo temporal em camundongos
(Universidade Federal de Santa Maria, 2015-03-16)
Epilepsy is a disease that affects about 1-2% of the general population. Considering the high number of patients with epilepsy who are refractory to currently available drugs, it is important to search for new anticonvulsant ...
Óleos essenciais como anestésicos para peixes: aspectos bioquímicos e moleculares
(Universidade Federal de Santa Maria, 2015-01-15)
The essential oil (EOs) extracted from plants Hesperozygis ringens and Lippia alba possess
anesthetic and sedative properties and is an alternative to traditional anesthetics used in
aquaculture for ease of handling ...