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Contribuição do sistema colinérgico e da sinalização do NRF2/HO-1 para a ação anti-amnésica do 7-flúor-1,3- difenilisoquinolina-1-amina em camundongos
(Universidade Federal de Santa Maria, 2019-07-26)
Dementia is a heterogenic condition characterized by different symptoms and theories about its pathogenesis, which results in difficult to understand and in the treatment of this disease. The 7-fluoro-1,3-diphenylisoquin ...
Estresse pré e pós natal afetam aspectos morfológicos, bioquímicos e moleculares do eixo cortico-hipotalâmico na prole adulta
(Universidade Federal de Santa Maria, 2019-10-18)
According to the World Health Organization (2010), stress is recognized and identified as the evil of the century due to its chronicity and repercussions that are directly connected to life quality, family and society. ...
Efeito neuroprotetor da Berberina na neurotoxicidade induzida por estreptozotocina e lipolissacarídeo em ratos
(Universidade Federal de Santa Maria, 2019-10-29)
Alzheimer's disease (AD) is considered the major cause of dementia and is characterized by changes in the cholinergic and purinergic system, oxidative stress, inflammatory process and metabolic changes that, in turn, are ...