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Triagem de cepas de Saccharomyces cerevisiae sensíveis ao metilglioxal
(Universidade Federal de Santa Maria, 2015-01-15)
Methylglyoxal is a very reactive α-dicarbonilic compound, that can can be formed in high concentrations in hyperglycemic conditions. It is produced mainly via non-enzymatic ways from glycolytic intermediates, like ...
Estudo da ação antipsicótica e efeitos colaterais do haloperidol nanoencapsulado em ratos
(Universidade Federal de Santa Maria, 2012-06-29)
Haloperidol is a typical neuroleptic widely used in the treatment of several psychotic disorders and it remains the most prescribed antipsychotic worldwide, due to its high potency and low cost. Despite its good therapeutic ...
Dexmedetomidina diminui a resposta inflamatória após cirurgia miocárdica sob mini-circulação extracorpórea
(Universidade Federal de Santa Maria, 2013-03-09)
Despite great technological advances in coronary artery bypass grafting (CABG) surgery, there is a high incidence of cardiac dysfunction and neurocognitive deficits in the postoperative period. Preventive measures are ...
Avaliação da atividade da isatina-3-N4-benziltiossemicarbazona (IBTC) como antioxidante na proteção da LDL contra a oxidação
(Universidade Federal de Santa Maria, 2012-08-10)
Several lines of evidence support the hypotheses that the oxidation of low density lipoprotein (LDL) is a proatherogenic factor. Oxidative stress is one of the causes of the overproduction of reactive species that increase ...
Produtos apícolas como antioxidantes em peixes frente a desafios oxidantes provocados por tebuconazole
(Universidade Federal de Santa Maria, 2013-10-25)
This paper present alternatives to mitigate the deleterious effects caused by pesticides from
crops that contaminate ponds and water bodies, located very close to the growing areas. This
proximity causes oxidative damage ...
2,2'-Disseleneto de ditienila, um composto orgânico de selênio com atividade antioxidante e neuroprotetora em ratos
(Universidade Federal de Santa Maria, 2012-03-02)
Oxidative stress has been implicated in the pathophysiology of several neurological
diseases since the brain is an organ highly susceptible to oxidative damage. Temporal lobe
epilepsy (TLE) has been widely studied due ...
Interações entre o estresse repetido e clomipramina: diferentes respostas em ratos machos e fêmeas
(Universidade Federal de Santa Maria, 2011-10-14)
Repeated stress or stressful events has been reported to induce anxiety and depression. Differential
responses to repeated stress and antidepressant treatments have been observed in males and females.
Clomipramine is a ...
Uncaria tomentosa: possível uso como adjuvante no tratamento do câncer cólon retal
(Universidade Federal de Santa Maria, 2011-09-23)
Reports of the use of cat's claw (Uncaria tomentosa) in patients with cancer, in conjunction with traditional therapies such as chemotherapy and radiotherapy, show decrease in adverse effects to these therapies (such as ...
Avaliação de parâmetros bioquímicos em jundiás expostos a três formulações comerciais de glifosato
(Universidade Federal de Santa Maria, 2013-08-16)
Due to the increase in food production in the last years, the use of pesticides has also increased significantly. These pesticides pollute aquatic ecosystems and harm non-target organisms, such as fish. Therefore, the aim ...
Efeitos dos compostos de selênio e zinco nas lesões gastrointestinais induzidas por etanol em ratos
(Universidade Federal de Santa Maria, 2012-03-30)
Gastric ulcer is a world widespread illness that affectes a great number of people and it is correlated to life style, food intake, alcohol and smoke in association or not to stress behavior. The lesions are in association ...