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Associação da via inflamatória e apoptótica na patofisiologia do acidente vascular encefálico tardio: relação com a dislipidemia
(Universidade Federal de Santa Maria, 2015-01-22)
Stroke occurs when blood flow to the brain is interrupted by an embolic or thrombotic occlusion of a cerebral artery (ischemic stroke) or by bleeding from a ruptured blood vessel (hemorrhagic stroke). Oxidative stress and ...
Efeito farmacogenético do polimorfismo Ala16Val do gene da MnSOD na resposta de pacientes hipercolesterolêmicos a rosuvastatina
(Universidade Federal de Santa Maria, 2015-02-27)
Rosuvastatin is used as a drug of first choice in treating hypercholesterolemia due to
competitive inhibition of HMG-CoA reductase enzyme which converts HMG-CoA to
mevalonic acid which is the rate-limiting step in ...
Marcadores inflamatórios, cardíacos e expressão de ectoenzimas do sistema purinérgicoem plaquetas de pacientes HIV positivos
(Universidade Federal de Santa Maria, 2016-04-25)
Recent studies have demonstrated that HIV infection and antiretroviral treatment may favor a procoagulant state and dyslipidemia, which contribute to developing cardiovascular diseases. Platelets are involved in heart ...
Ação antinociceptiva e anti-inflamatória da fração acetato de etila da casca da Scutia buxifolia Reiss em camundongos
(Universidade Federal de Santa Maria, 2016-02-12)
Pain and inflammation are physiological processes, which when persist can be harmful to health. The pain when improperly or left untreated can become chronic pain. Moreover, the inflammation can be involved in the pathogenesis ...
Citocinas inflamatórias na urina como indicadores de dano renal em pacientes com diabetes mellitus tipo 2
(Universidade Federal de Santa Maria, 2016-12-20)
Diabetic kidney disease (DKD) is a highly prevalent microvascular complication in patients with diabetes mellitus (DM) and is the leading cause of end-stage renal disease in most countries. Until now, urinary albumin ...
Efeito da atorvastatina sobre as alterações comportamentais, histológicas e bioquímicas em camundongos C57BL/6 com status epilepticus induzido por pilocarpina
(Universidade Federal de Santa Maria, 2017-03-06)
Epilepsy is a chronic neurological disease that affects 65 million people worldwide. Temporal
lobe epilepsy (TLE) is the most common type of focal epilepsy in adults, and also the one
with the highest refractoriness index ...
Investigação dos mecanismos associados ao efeito cicatrizante e regenerativo do barbatimão (Stryphnodendron adstringens) em modelos celulares in vitro
(Universidade Federal de Santa Maria, 2019-03-11)
Introduction: The skin is the largest organ of the human body and has the functions of coat, delimitate, protec and interact with the external environment. Skin lesions affect the general population, regardless of gender, ...
Molécula de dano renal-1 na urina e sua associação com o controle glicêmico e com a concentração urinária das interleucinas 1 e 6 no diabetes tipo 2
(Universidade Federal de Santa Maria, 2018-08-17)
Diabetes kidney disease (DRD) is among the main and most relevant complications of diabetes mellitus (DM). Hyperglycemia and inflammation are two of several factors involved in the development and progression of DM ...
Chenopodium ambrosioides L. do uso popular aos ensaios pré-clínicos: análise química, potencial anti-inflamatório e estudo da toxicidade
(Universidade Federal de Santa Maria, 2019-08-19)
Chenopodium ambrosioides L., popularly known as Erva-de-Santa-Maria, is widely used in folk medicine against many diseases, as anti-inflammatory, healing, among others. In 2009, it was inserted in RENISUS, due to its wide ...
Influência de fatores farmacológicos e nutricionais na resposta oxidativa-inflamatória in vitro induzida pela olanzapina
(Universidade Federal de Santa Maria, 2019-03-13)
Introduction: Olanzapine (OLZ) is a second generation antipsychotic (ASG) used in the treatment of
schizophrenia, bipolar disorder and other neuropsychiatric conditions. The adverse effects of ASG
include ...