Buscar
Itens para a visualização no momento 11-20 of 25
Efeito neuroprotetor da Berberina na neurotoxicidade induzida por estreptozotocina e lipolissacarídeo em ratos
(Universidade Federal de Santa Maria, 2019-10-29)
Alzheimer's disease (AD) is considered the major cause of dementia and is characterized by changes in the cholinergic and purinergic system, oxidative stress, inflammatory process and metabolic changes that, in turn, are ...
Efeito amnésico da arcaína depende da novidade e do sistema opióide
(Universidade Federal de Santa Maria, 2012-03-01)
Previous exposure to the training context disrupts glutamatergic N-methyl-Daspartate
receptor (NMDAr) antagonist-induced amnesia, indicating that novelty is
necessary for such an amnestic effect. While there are reports ...
Envolvimento do sistema opióide na dependência de estado induzida pela arcaína em ratos
(Universidade Federal de Santa Maria, 2011-03-02)
Arcaine is a competitive antagonist of the polyamine binding site at the NMDA receptor which induces state-dependent recall. However, no study has addressed the involvement of other neurotransmitter/neuromodulators ...
Espermina reverte o dano de memória induzido por lipopolissacarídeo em camundongos
(Universidade Federal de Santa Maria, 2014-08-21)
Neuroinflammation is a neuropathological finding in a number of neurodegenerative diseases. Intraperitoneal injection of lipopolysaccharide (LPS) induces neuroinflammation and memory deficit. Spermine and spermidine are ...
Avaliação dos efeitos de drogas anti-adenosinérgicas e do disseleneto de difenila no prejuízo da memória e estresse oxidativo relacionados ao envelhecimento
(Universidade Federal de Santa Maria, 2012-08-08)
Biological aging is gradual and progressive decline of physical functions that begin in adulthood and ends with death in almost all animals species. One of the most common features of aging is the reduced ability to learn ...
Avaliação neuropsicológica e dos marcadores inflamatórios nos pacientes com epilepsia
(Universidade Federal de Santa Maria, 2015-08-31)
The epilepsy is a neurological disorder manifested by recurrent unprovoked
seizures, resulting in harmful effects on the patients. Epileptic seizures are generated
from hypersincronic abnormal discharges of neurons, ...
4,4'-dicloro-difenil disseleneto reverte o déficit de memória induzido pela corticosterona em camundongos
(Universidade Federal de Santa Maria, 2016-02-29)
Chronic stress or even a single serious traumatic experience may have a negative impact on cognitive function. In this sense, organic selenium compounds are molecules that arouse great interest because they have various ...
Cafeína suprime a melhora na memória de longa duração e de localização induzida pelo exercício em ratos de meia-idade
(Universidade Federal de Santa Maria, 2014-07-29)
The cognitive function decline is closely related with brain changes generated by age. The ability of caffeine and exercise to prevent memory impairment has been reported in animal models and humans. The purpose of the ...
Avaliações neuroquímicas, enzimáticas e comportamentais em ratos infectados experimentalmente com trypanosoma evansi e utilização da curcumina como possível agente terapêutico
(Universidade Federal de Santa Maria, 2013-05-20)
The pathogenesis of Trypanosoma evansi (T. evansi) infection on central and peripheral nervous
system (CNS) and immunologic system it is not completely understood. This study was conducted to
investigate the effects of ...
Papel protetor do 2-feniletinil-butilterúrio em modelos de dano cognitivo em camundongos e na apoptose em células humanas
(Universidade Federal de Santa Maria, 2013-03-27)
Memory is considered to be a process that has several stages, including acquisition, consolidation and retrieval.
Memory impairment occurs when important synapses are modified. Alzheimer s disease (DA) is the most
common ...