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Investigação da atividade antioxidante in vitro e da composição química de diferentes extratos de plantas medicinais
(Universidade Federal de Santa Maria, 2011-03-18)
Oxidative stress (OS) is involved in the development of several disorders involving the central nervous system, such as Alzheimer s disease (AD). Considering the limitations of current therapeutics for AD, there is still ...
Envolvimento do sistema da tiorredoxina nas alterações induzidas pelo chumbo in vitro e in vivo: implicações na toxicidade do chumbo
(Universidade Federal de Santa Maria, 2011-11-30)
Oxidative stress is an important molecular mechanism of lead (Pb) toxicity. The thioredoxin
system (selenoenzyme thioredoxin reductase-TrxR, thioredoxin protein- Trx and NADPH) is essential
for the antioxidant defense ...
Avaliação dos efeitos biológicos do (s) (3-feniltelanil propanamida) succinato de dimetila, um novo telúrio aminoácido derivado do ácido aspártico
(Universidade Federal de Santa Maria, 2011-03-25)
Recent studies from our group demonstrated that the (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate compound, a telluroamino acid showed glutathione peroxidase (GPx)-like activity, attesting to its antioxidant ...
Efeitos benéficos do extrato das cascas de noz pecã (Carya illinoensis) sobre parâmetros bioquímicos e comportamentais de camundongos expostos ao fumo passivo
(Universidade Federal de Santa Maria, 2011-01-28)
Smoking is the second major reason of death worldwide, amounting 5 millions
of deaths annually. The adverse effects of cigarette smoking are not limited to active
smokers, but also to passive smokers, which comprise one ...
Quantificação de α-tocoferol, retinol e carotenóides e seus possíveis efeitos sobre a peroxidação lipídica em trabalhadores expostos a solventes
(Universidade Federal de Santa Maria, 2011-02-18)
Oxidative stress is a process characterized by the antioxidant defense system
decrease and/or an excessive reactive species (RS) production. RS are substances
capable of attacking proteins, lipids and DNA. The oxidative ...
Influência do polimorfismo Ala16Val do gene da enzima superóxido dismutase (SOD2) no efeito antioxidante in vitro do citrato de clomifeno
(Universidade Federal de Santa Maria, 2011-08-16)
To investigate the in vitro antioxidant properties of the ovulation induction drug,
Citrate clomiphene (CC), and to access whether its effects are influenced by the
Ala16Val polymorphism in the SOD2 gene, which encodes ...
Efeitos do exercício físico sobre parâmetros de estresse oxidativo em ratos hipertensos
(Universidade Federal de Santa Maria, 2011-09-05)
Hypertension has been regarded as one of the most important factors associated with the
development of vascular disease and is closely linked to increased reactive oxygen species (ROS). In
contrast, exercise has been ...
Efeitos da rutina sobre a atividade da aceticolinesterase e sobre o comportamento em ratos expostos ao cádmio
(Universidade Federal de Santa Maria, 2011-09-09)
This study investigated the effect of administration of cadmium (Cd), Rutin (Rut), or both, on lipid peroxidation in different brain structures, memory, anxiety and activity of the enzyme acetylcholinesterase (AChE) (ex ...
Ácido húmico e hipóxia moderada alteram parâmetros oxidativos e fisiológicos em diferentes tecidos de jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2011-12-15)
The aquatic environment presents different levels of dissolved oxygen (DO) and
humic substances (HS), which are compounds derived from organic biomass in
decomposition. The HS are composed of humic acid (HA), fulvic acids ...
Interações entre o estresse repetido e clomipramina: diferentes respostas em ratos machos e fêmeas
(Universidade Federal de Santa Maria, 2011-10-14)
Repeated stress or stressful events has been reported to induce anxiety and depression. Differential
responses to repeated stress and antidepressant treatments have been observed in males and females.
Clomipramine is a ...