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Avaliação dos efeitos de compostos orgânicos de selênio e de telúrio sobre a integridade estrutural e funcional de células sangüíneas humanas
(Universidade Federal de Santa Maria, 2009-01-09)
In view of the need to expand the toxicologic studies of organochalcogens in biological systems, the aim of this study was to investigate the effect of exposure to
organic compounds of selenium (Se) and tellurium (Te) on ...
Efeito inibitório do Ebselen, do disseleneto de difenila e do ditelureto de difenila sobre a atividade da LDH de mamíferos
(Universidade Federal de Santa Maria, 2009-02-09)
Ebselen is a seleno compound whose antioxidant properties have been
attributed to its thiol-peroxidase and thioredoxin-like activity: it decomposes
peroxides at the expense of reduced thiols. However, the excessive ...
Avaliação dos mecanismos envolvidos na ação antinociceptiva causada pelo seleneto vinílico bis substituído (SVBS) em camundongos
(Universidade Federal de Santa Maria, 2009-03-24)
The interest in organoselenium biochemistry and pharmacology has increased in the last two decades due to a variety of organoselenium compounds that possess biological activity. Accordingly, bis selenide is known as a safe ...
Atividade hipolipidêmica do disseleneto de difenila na hiperlipidemia induzida por Triton WR-1339 em camundongos
(Universidade Federal de Santa Maria, 2009-11-26)
In mammals, the liver plays a central role in whole-body lipid metabolism. Unfortunately, dysregulation of these pathways has been implicated in hyperlipidemias. In recent years, a significant association between the trace ...
Mecanismos envolvidos no efeito antioxidante do disseleneto de difenila no dano oxidativo causado pela exposição à fumaça do cigarro em ratos jovens
(Universidade Federal de Santa Maria, 2009-09-09)
Cigarette smoking is a complex mixture of many constituents identified, among them reactive substances (reactive oxygen and nitrogen species), which are capable of initiating or promoting oxidative damage. Lungs and brain ...
Efeito hepatoprotetor causado pelo 3-alquinil selenofeno contra o dano oxidativo induzido por agentes químicos em ratos
(Universidade Federal de Santa Maria, 2009-02-16)
The liver presents extraordinary functional diversity, particularly in the control of energy production, immune defense and volemic reserve. The human being is exposed
occupationally and in the environment to a variety ...