Several pathophysiological mechanisms are associated with type 2 diabetes mellitus (type 2 DM), such as glucotoxicity, insulin resistance, inflammation, oxidative stress and endothelial dysfunction, which can result in DNA ...

The advanced oxidation protein products (AOPPs) are a new class of compounds identified as markers of oxidative damage to proteins. The physiology role of these products is not limited to assess the oxidative stress, and ...

Metabolic syndrome (MetS) is a complex disorder represented by a set of cardiovascular risk factors, including endothelial dysfunction, oxidative stress and inflammation. Syzygium cumini has hypoglycemic, anti-inflammatory, ...

The gout is an extremely painful type of arthritis. Despite the large number of drugs available for its treatment, they usually cause many adverse effects that limit their use. Then, further investigations are necessary ...

This study aimed to analyze the association between the genetic polymorphism of the manganese-dependent superoxide dismutase (Ala16Val MnSOD) and the oxidative and inflammatory markers in hypercholesterolemic and control ...

The intake of flavonoids is closely associated with diminished risks of cancer, atherosclerosis and other chronic inflammation disturbance related. These compounds are described, mainly, by their anti-inflammatory and ...

The interest in organoselenium biochemistry and pharmacology has increased in the last two decades due to a variety of organoselenium compounds that possess biological activity. Accordingly, diphenyl diselenide, a simple ...

Despite great technological advances in coronary artery bypass grafting (CABG) surgery, there is a high incidence of cardiac dysfunction and neurocognitive deficits in the postoperative period. Preventive measures are ...

Exercise can represent a physical stress that disrupts the homeostasis. Elevated muscle oxygen consumption increases reactive oxygen species (ROS) and inflammatory proteins production, leading to oxidative stress and ...

The regular practice of physical exercise is linked to a good life quality. However, each physical bout has consequences named reactive oxygen species (ROS) production, low-grade inflammation, delayed onset muscle soreness ...