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Dano ao DNA no diabetes tipo 2 e sua associação com inflamação, estresse oxidativo, disfunção endotelial, resistência à insulina e à ocorrência de complicações crônicas microvasculares
(Universidade Federal de Santa Maria, 2016-03-15)
Several pathophysiological mechanisms are associated with type 2 diabetes mellitus (type 2 DM), such as glucotoxicity, insulin resistance, inflammation, oxidative stress and endothelial dysfunction, which can result in DNA ...
FORMAÇÃO DE PRODUTOS PROTEICOS DE OXIDAÇÃO AVANÇADA A PARTIR DA REAÇÃO DE FENTON E COLÁGENO: EFEITOS SOBRE PROCESSOS INFLAMATÓRIOS EM NEUTRÓFILOS E CÉLULAS RENAIS EMBRIONÁRIAS
(Universidade Federal de Santa Maria, 2016-07-05)
The advanced oxidation protein products (AOPPs) are a new class of compounds identified as markers of oxidative damage to proteins. The physiology role of these products is not limited to assess the oxidative stress, and ...
Efeito do extrato de Syzygium cumini e alterações provocadas pela síndrome metabólica sobre parâmetros bioquímicos e inflamatórios
(Universidade Federal de Santa Maria, 2013-12-04)
Metabolic syndrome (MetS) is a complex disorder represented by a set of cardiovascular risk factors, including endothelial dysfunction, oxidative stress and inflammation. Syzygium cumini has hypoglycemic, anti-inflammatory, ...
PAPEL DO TRPV1 EM UM MODELO ARTICULAR DE GOTA AGUDA EM RATOS
(Universidade Federal de Santa Maria, 2014-02-17)
The gout is an extremely painful type of arthritis. Despite the large number of drugs available for its treatment, they usually cause many adverse effects that limit their use. Then, further investigations are necessary ...
Polimorfismo da Ala16Val MnSOD na hipercolesterolemia e sua associação com biomarcadores de inflamação e estresse oxidativo
(Universidade Federal de Santa Maria, 2010-03-11)
This study aimed to analyze the association between the genetic polymorphism of the manganese-dependent superoxide dismutase (Ala16Val MnSOD) and the oxidative and inflammatory markers in hypercholesterolemic and control ...
Mecanismos envolvidos na ação antinociceptiva e antiinflamatória do flavonóide miricitrina: estudos in vivo e in vitro"
(Universidade Federal de Santa Maria, 2006-05-02)
The intake of flavonoids is closely associated with diminished risks of cancer, atherosclerosis and other chronic inflammation disturbance related. These compounds are described, mainly, by their anti-inflammatory and ...
Estudos dos mecanismos envolvidos na ação antinociceptiva causada pelo disseleneto de difenila em camundongos
(Universidade Federal de Santa Maria, 2007-08-01)
The interest in organoselenium biochemistry and pharmacology has increased in the last two decades due to a variety of organoselenium compounds that possess biological activity. Accordingly, diphenyl diselenide, a simple ...
Dexmedetomidina diminui a resposta inflamatória após cirurgia miocárdica sob mini-circulação extracorpórea
(Universidade Federal de Santa Maria, 2013-03-09)
Despite great technological advances in coronary artery bypass grafting (CABG) surgery, there is a high incidence of cardiac dysfunction and neurocognitive deficits in the postoperative period. Preventive measures are ...
Efeitos da cafeína e do diclofenaco sobre o estresse oxidativo e a inflamação em ratos submetidos ao exercício físico
(Universidade Federal de Santa Maria, 2015-07-01)
Exercise can represent a physical stress that disrupts the homeostasis. Elevated muscle oxygen consumption increases reactive oxygen species (ROS) and inflammatory proteins production, leading to oxidative stress and ...
Efeitos do treinamento aeróbico no processo inflamatório e estresse oxidativo no córtex e músculo e a sua relação com exercícios à exaustão, bem como as adaptações causadas pelo treinamento aeróbico no fígado de ratos
(Universidade Federal de Santa Maria, 2015-01-08)
The regular practice of physical exercise is linked to a good life quality. However, each
physical bout has consequences named reactive oxygen species (ROS) production, low-grade
inflammation, delayed onset muscle soreness ...