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Estudo de métodos cromatográficos e ensaio biológico para avaliação do anticorpo monoclonal denosumabe
(Universidade Federal de Santa Maria, 2017-07-27)
Denosumab (DmAb) is a fully human monoclonal antibody that inhibits osteoclast formation, function and survival, reducing bone turnover and resorption. Structurally, it is a fully human immunoglobulin G2, yielding a molecular ...
Avaliação de potência de interferon beta -1b por métodos cromatográficos validados e bioensaio
(Universidade Federal de Santa Maria, 2017-07-27)
Interferon is a cytokine with antiviral, antiproliferative and immunomodulatory properties that influences cell metabolism, growth and differentiation. The recombinant human interferon β 1b (rhIFNβ-1b) is a non-glycosylated ...
Validação de métodos cromatográficos para avaliação de estreptoquinase e correlação com o bioensaio
(Universidade Federal de Santa Maria, 2016-03-30)
The streptokinase (STK) is a secreted and isolated molecule of β-hemolytic streptococci,
consists of 414 amino acids and clinically indicated as a thrombolytic agent for myocardial
infarction, deep vein thrombosis, ...
Desenvolvimento e validação de método por cromatografia líquida em fase reversa para análise de rivaroxabana
(Universidade Federal de Santa Maria, 2015-02-27)
Rivaroxaban is an oral anticoagulant drug indicated for deep venous thromboembolism prophylaxis. A reversed-phase liquid chromatography (RP-LC) method was developed and validated for the determination of rivaroxaban in ...
Prevalência de diabetes mellitus em indivíduos portadores de periodontite em uma área rural do Sul do Brasil
(Universidade Federal de Santa Maria, 2018-07-27)
The objective of this study is to evaluate the prevalence of patients with diabetes among the individuals diagnosed with periodontitis using a threshold level that allows identifying more severe cases with considerable ...
Cuidado ao familiar cuidador de idosos: contribuições da prática educativa para a qualificação multiprofissional
(Universidade Federal de Santa Maria, 2019-09-30)
Cuidados relativos a sexualidade na voz de idosos e de enfermeiros
(Universidade Federal de Santa Maria, 2019-12-10)
Sexuality is a relevant aspect in the life of the elderly person, but not always considered, at the time of providing care, by the professional nurse. The study aimed to understand the aspects related to nursing care about ...
Atenção primária e doença falciforme: papel do gestor
(Universidade Federal de Santa Maria, 2014-07-07)
The hemoglobinophaties are the main and more frequent genetic disease that affect humans, being the sickle cell disease very relevant in the context of public health in Brazil. Aspects related to public health are extrated ...
Risco de quedas e níveis de fragilidade em idosos que fazem uso de ansiolíticos e/ou antidepressivos
(Universidade Federal de Santa Maria, 2017-10-23)
This research aimed to study the risk of falls and the levels of fragility in the elderly who use anxiolytics and / or antidepressants. This is a cross-sectional, analytical cross-sectional study involving elderly individuals ...
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos
(Universidade Federal de Santa Maria, 2015-08-17)
The non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in Endodontics and when associated with some risk factors, such as concomitant use of other drugs, may develop undesirable and possibly serious effects. ...