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Atividade de ectoenzimas do sistema purinérgico e análise de biomarcadores inflamatórios e de estresse oxidativo em pacientes com câncer de pulmão
(Universidade Federal de Santa Maria, 2014-11-13)
Lung cancer has been considered a public health problem since it has become one of the most commonly diagnosed neoplastic diseases and one of the most lethal in the world. This spread of lung cancer in the world population ...
Constituintes químicos e propriedades bioativas de Lantana montevidensis (spreng.) briq. e Lantana camara L. (verbenaceae): evidências para o uso farmacológico
(Universidade Federal de Santa Maria, 2016-04-08)
Humans have been using medicinal plants for centuries as preventive or curative agents. In
Brazil, the use of plants in the treatment of diseases is influenced by Indigenous, African and
European cultures. Among these ...
Efeito farmacológico do disseleneto de m-trifluormetil-fenila na comorbidade entre dor e depressão em camundongos
(Universidade Federal de Santa Maria, 2015-07-24)
Chronic pain and depression often coexist, and several mechanisms are involved in the pathogenesis of this comorbidity, which confer it resistance to treatment. The serotonergic system is considered a central mechanism in ...
Efeito in vitro do extrato de Solanum sessiliflorum: atividade antioxidante e antitumoral (MCF-7 e HT29)
(Universidade Federal de Santa Maria, 2015-11-05)
Epidemiological studies have suggested that intake of fruits and vegetables act in the prevention of several diseases such as cancer and cardiovascular diseases. This can be explained by these bioactive compounds are present ...
Efeitos biológicos do óleo essencial e do extrato hidro alcóolico das folhas de Psidium guajava var. pomifera L.
(Universidade Federal de Santa Maria, 2015-12-17)
The Myrtaceae family has 145 genera. In Brazil are recorded 23 genera and about 1,013 species. Several plants of this family are used in food stuffs, for example, Psidium guajava L. fruits, commonly known as guava. In folk ...
Efeitos do resveratrol, do suco de uva e do vinho tinto nos biomarcadores de estresse oxidativo e na atividade de ectoenzimas em ratos diabéticos
(Universidade Federal de Santa Maria, 2012-11-28)
Diabetes mellitus is a major public health problem throughout the world. The chronic hyperglycemia present in the diabetic state is associated with increase of oxidative stress, which has been appointed to play a central ...
Avaliação anatomopatológica de fígado, rim, pulmão e cérebro de camundongos expostos ao composto ditelureto de difenila
(Universidade Federal de Santa Maria, 2014-08-29)
Diphenyl ditelluride (PhTe)2 is an organic tellurium compound widely used as an intermediate in organic synthesis reactions and in the industry. Several studies have shown that this compound causes various toxic effects ...
Efeitos metabólicos do consumo da castanha do Brasil (Bertholletia excelsa) em humanos saudáveis
(Universidade Federal de Santa Maria, 2014-02-25)
Brazil nut (Bertholletia excelsa, Lecythidaceae family) is the richest known food in selenium. Its consumption has demonstrated efficient in improving the lipid profile and the plasmatic selenium levels as well as to ...
Ação farmacológica do 3-alquinil selenofeno em modelos de convulsão em ratos jovens
(Universidade Federal de Santa Maria, 2012-03-02)
Seizures have important consequences in terms of mortality and quality of life of the affected population, being a risk factor for the development of cognitive and behavioral abnormalities. Considering the promising ...
Avaliação do potencial terapêutico da Valeriana officinalis e do disseleneto de difenila frente à toxicidade induzida por rotenona em Drosophila melanogaster
(Universidade Federal de Santa Maria, 2012-03-02)
Among various antioxidant therapeutic applications, neuroprotective action is highlighted sinceoxidative stress is recognized as one of the events involved in cell damage which occur in most of neurological disorders, ...