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Oleorresina de copaíba apresenta atividade antinociceptiva tópica em um modelo de queimadura de pele induzido por radiação UVB em camundongos
(Universidade Federal de Santa Maria, 2020-11-27)
Burn injuries are common worldwide, representing a major public health problem responsible for more than 180,000 deaths annually. These injuries can be caused by several factors, including ultraviolet (UV) radiation. ...
Fibras musculares oxidativas e glicolíticas apresentam resposta inflamatória e alterações bioenergéticas peculiares após uma contusão musculoesquelética em ratos
(Universidade Federal de Santa Maria, 2021-02-19)
Muscle contusion represents a type of stress that disrupts cell homeostasis. Characterized by traumatic lesion, that impair the availability of oxygen (O2) in the tissue, promotes an increase in the production of reactive ...
Lacunas na evolução da via de reparo por excisão de nucleotídeos em eucariotos
(Universidade Federal de Santa Maria, 2020-10-21)
Nucleotide excision repair (NER) is the most versatile DNA repair pathway as it
removes different kinds of bulky lesions. Due to its essential role for genome integrity,
it appeared early in the evolution of species. ...
Avaliação da barata Nauphoeta cinerea como organismo modelo para o estudo de sepse
(Universidade Federal de Santa Maria, 2020-11-05)
Studies using model organisms, such as insects, are growing and have sought to investigate, in
a preliminary way, the mechanisms involved in the progression of infectious diseases,
examine potential pharmacological targets ...
Caracterização dos genes que codificam selenoproteínas em peixe-zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2020-02-21)
Selenoproteins are selenocysteine (Sec)-containing proteins that exhibit numerous physiological functions, including redox homeostasis maintenance, thyroid hormones metabolism, selenium transport and chaperone-like activities. ...
Envolvimento dos receptores NMDA e imidazolínicos nos efeitos das poliaminas sobre a preferência condicionada por lugar induzida por morfina
(Universidade Federal de Santa Maria, 2020-01-30)
Morphine use disorder is a chronic disease involving biological, cognitive and behavioral changes that develop
after repeated and compulsive substance use. Even after long periods of abstinence relapses occur to ...
Taxonomia e biologia populacional de duas espécies simpátricas de Hyalella (Crustacea, Amphipoda, Hyalellidae)
(Universidade Federal de Santa Maria, 2020-02-18)
Freshwater amphipods of the genus Hyalella are typical in American continental waters and have
high levels of endemicity. In Brazil, the state of Rio Grande do Sul has the greatest diversity of
species for the genus known ...
Modelagem do fenótipo de diabetes em Nauphoeta cinerea usando estreptozotocina: Foco no metabolismo da glicose no cérebro
(Universidade Federal de Santa Maria, 2021-05-16)
The brain is highly dependent on adequate glucose catabolism, but changes in brain glucose transport are well documented in hyperglycemic conditions. Recent evidence of “hyperglycemic memory" further suggests that chronic ...
Atividade de vocalização de Crossodactylus schmidti (Anura: hylodidae) sob a influência da radiação ultravioleta
(Universidade Federal de Santa Maria, 2020-09-04)
Anthropogenic activities, such as the release of polluting gases and deforestation, accelerate the stratospheric ozone depletion increasing the incidence of ultraviolet radiation (UVR). Even though essential for life, UVR ...
Potencial fitorremediador para cromo de Handroanthus chrysotrichus (Mart. ex DC.) Mattos e Handroanthus heptaphyllus (Vell.) Mattos
(Universidade Federal de Santa Maria, 2020-01-30)
Brazil and the world have been facing serious soil contamination problems in the last decade. Among the numerous contaminants are heavy metals, which in turn may or may not be essential for human and plants development. ...