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Efeitos do resveratrol, do suco de uva e do vinho tinto nos biomarcadores de estresse oxidativo e na atividade de ectoenzimas em ratos diabéticos
(Universidade Federal de Santa Maria, 2012-11-28)
Diabetes mellitus is a major public health problem throughout the world. The chronic hyperglycemia present in the diabetic state is associated with increase of oxidative stress, which has been appointed to play a central ...
Ação farmacológica do 3-alquinil selenofeno em modelos de convulsão em ratos jovens
(Universidade Federal de Santa Maria, 2012-03-02)
Seizures have important consequences in terms of mortality and quality of life of the affected population, being a risk factor for the development of cognitive and behavioral abnormalities. Considering the promising ...
Ratas lactantes e não lactantes diferem quanto à sensibilidade ao HgCl2: efeito protetor do ZnCl2
(Universidade Federal de Santa Maria, 2012-08-17)
Mercury is a divalent metal found in the liquid state at room temperature without biological function. Occupational exposure to this metal occurs mainly in industrial activities and agriculture. Its toxicity seems to be ...
Dieta suplementada com disseleneto de difenila atenua as alterações bioquímicas e comportamentais no modelo de hipotireoidismo induzido por metimazol
(Universidade Federal de Santa Maria, 2012-12-14)
Hypothyroidism is a syndrome resulting from decreased production and secretion of triiothyronine (T3) and thyroxine (T4) hormones, frequently diagnosed in women. Clinical and experimental evidence support the association ...
Efeito toxicogenético do polimorfismo Ala16Val do gene MnSOD em leucócitos expostos in vitro ao metil mercúrio
(Universidade Federal de Santa Maria, 2012-03-19)
The environmental contamination by methyl mercury (MeHg) is a great health public problem in
some world regions like Amazonia. The MeHg toxic effects seem to be influenced by
environmental and genetic factors. However, ...
Respostas bioquímicas em carpas (Cyprinus carpio) expostas a duas formulações comerciais de inseticidas em condições de lavoura de arroz e em laboratório
(Universidade Federal de Santa Maria, 2012-07-27)
The pesticides are substances widely used in agriculture, because it enhances productivity. However, its excessive and disordered use has caused different impacts on the environment. Therefore, this study investigated the ...
Frutose-1,6-bisfosfato e N-acetilcisteína atenuam a formação de produtos proteicos de oxidação avançada, uma nova classe de mediadores inflamatórios, in vitro
(Universidade Federal de Santa Maria, 2012-09-19)
The assessment of biomarkers of reactions involving reactive oxygen species have the
potential not only to determine the extent of oxidative damage, but also to predict the
effectiveness of therapeutic strategies aimed ...
Efeito do decocto de Bauhinia forficata sobre parâmetros comportamentais e metabólicos em ratos tratados com haloperidol
(Universidade Federal de Santa Maria, 2012-09-27)
Schizophrenia is a psychiatric disorder that affects 1% of world population and its pharmacologic treatment consists in the use of antipsychotics. It is known that chronic treatment with classical antipsychotics, such as ...
Atividade de ectoenzimas e de colinesterases e biomarcadores de estresse oxidativo em pacientes com câncer de pulmão
(Universidade Federal de Santa Maria, 2012-03-02)
Lung cancer has become one of the most commonly diagnosed neoplastic diseases, as well as one of the most lethal worldwide, characterized, therefore, as a public health problem. This spread of lung cancer in the world ...
Efeitos do disseleneto de difenila sobre o dano oxidativo causado por paracetamol em cérebro de camundongos
(Universidade Federal de Santa Maria, 2012-06-11)
Acetaminophen (APAP) is the analgesic most used in world, in therapeutic doses does not show toxicity, but in elevated doses can cause hepatic damage due the formation of his metabolic toxic N-acetyl-p-benzoquinonimine ...