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Estudo de mecanismos de toxicidade do metilmercúrio: papel protetor de flavonóides
(Universidade Federal de Santa Maria, 2010-08-12)
Methylmercury (MeHg) is an important environmental toxicant that may cause irreversible neurobehavioral and neuropsychological disorders in humans and experimental animals. The major mechanisms of MeHg-induced toxicity ...
Envolvimento do sistema da tiorredoxina nas alterações induzidas pelo chumbo in vitro e in vivo: implicações na toxicidade do chumbo
(Universidade Federal de Santa Maria, 2011-11-30)
Oxidative stress is an important molecular mechanism of lead (Pb) toxicity. The thioredoxin
system (selenoenzyme thioredoxin reductase-TrxR, thioredoxin protein- Trx and NADPH) is essential
for the antioxidant defense ...
Avaliação dos efeitos de um campo magnético pulsado sobre a cicatrização cutânea e biomarcadores oxidativos em ratos wistar
(Universidade Federal de Santa Maria, 2015-08-14)
The surgical postoperative period requires rapid, effective and good-quality wound repair. For a better cicatrization process alternatives have been sought to assist wound repair and improve the appearance of scarred region. ...
Avaliação do potencial antioxidante dos extratos aquoso e etanólico de Mentha pulegium, Uncaria tomentosa e Phyllanthus niruri frente às alterações induzidas por T-butil hidroperóxido em eritrócitos humanos in vitro
(Universidade Federal de Santa Maria, 2016-07-27)
The stone cruscher (Phyllanthus niruri), cat'sclaw (Uncaria tomentosa) and pennyroyal (Mentha pulegium)have been used by people to treat a variety of diseases associated with oxidative stress. In this study, we aimed to ...
Efeito do ácido cafeico e ácido cafeico fenetil éster em modelo de inflamação induzida por lipopolisacarídeo
(Universidade Federal de Santa Maria, 2016-08-05)
Peripheral inflammation is able to cause alterations in central nervous system (CNS) and lead to progression of neurodegenerative diseases. During neuroinflammatory process the activation of immune cells from the CNS and ...
Estudo clínico, randomizado, controlado por placebo do efeito da suplementação de açaí em marcadores associados ao zumbido crônico
(Universidade Federal de Santa Maria, 2020-07-31)
Introduction: Chronic tinnitus is a subjective multifactorial symptom, in which different treatments are proposed for its management, antioxidants have been shown as an apparently promising perspective. Açaí extract, made ...
Quantificação de α-tocoferol, retinol e carotenóides e seus possíveis efeitos sobre a peroxidação lipídica em trabalhadores expostos a solventes
(Universidade Federal de Santa Maria, 2011-02-18)
Oxidative stress is a process characterized by the antioxidant defense system
decrease and/or an excessive reactive species (RS) production. RS are substances
capable of attacking proteins, lipids and DNA. The oxidative ...
Efeito do resveratrol e da vitamina E frente a prejuízos reprodutivos causados pelo uso de ácido valpróico em ratos machos
(Universidade Federal de Santa Maria, 2016-08-31)
Long-term treatment with valproic acid (VPA) has been associated with adverse effects
on the male reproductive function mediated by increased testicular oxidative stress.
Thus, this study evaluated the potential protective ...
Avaliação do estresse oxidativo e da atividade da enzima d-aminolevulinato desidratase em pacientes transplantados de medula óssea
(Universidade Federal de Santa Maria, 2008-12-19)
Bone marrow transplantation (BMT) has been used in the treatment of a number of
diseases. Before BMT, patients are submitted to a conditioning regime (CR) that consists of
administration of high doses of chemo- or ...
Vitamina C plasmática está negativamente associada com a atividade das aminotransferases em pacientes com hepatite C não tratados
(Universidade Federal de Santa Maria, 2007-04-20)
In this study, the possible relationship between aminotransferase activities and markers of oxidative stress in hepatitis C patients was evaluated. Patients with HCV
(hepatitis C virus) infection confirmed by positive HCV ...