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Investigação da atividade antioxidante in vitro e da composição química de diferentes extratos de plantas medicinais
(Universidade Federal de Santa Maria, 2011-03-18)
Oxidative stress (OS) is involved in the development of several disorders involving the central nervous system, such as Alzheimer s disease (AD). Considering the limitations of current therapeutics for AD, there is still ...
Envolvimento do sistema da tiorredoxina nas alterações induzidas pelo chumbo in vitro e in vivo: implicações na toxicidade do chumbo
(Universidade Federal de Santa Maria, 2011-11-30)
Oxidative stress is an important molecular mechanism of lead (Pb) toxicity. The thioredoxin
system (selenoenzyme thioredoxin reductase-TrxR, thioredoxin protein- Trx and NADPH) is essential
for the antioxidant defense ...
Efeito do cobre e do selenito de sódio no estresse oxidativo, proteínas séricas e carga parasitária de cordeiros infectados experimentalmente por Haemonchus contortus
(Universidade Federal de Santa Maria, 2011-03-25)
This study aimed to evaluate the oxidative status and electrophoresis of sheep experimentally infected with Haemonchus contortus and supplemented with selenium and copper. We used 28 Corriedale and Texel crossbred lambs ...
Avaliação dos efeitos biológicos do (s) (3-feniltelanil propanamida) succinato de dimetila, um novo telúrio aminoácido derivado do ácido aspártico
(Universidade Federal de Santa Maria, 2011-03-25)
Recent studies from our group demonstrated that the (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate compound, a telluroamino acid showed glutathione peroxidase (GPx)-like activity, attesting to its antioxidant ...
Efeitos benéficos do extrato das cascas de noz pecã (Carya illinoensis) sobre parâmetros bioquímicos e comportamentais de camundongos expostos ao fumo passivo
(Universidade Federal de Santa Maria, 2011-01-28)
Smoking is the second major reason of death worldwide, amounting 5 millions
of deaths annually. The adverse effects of cigarette smoking are not limited to active
smokers, but also to passive smokers, which comprise one ...
Quantificação de α-tocoferol, retinol e carotenóides e seus possíveis efeitos sobre a peroxidação lipídica em trabalhadores expostos a solventes
(Universidade Federal de Santa Maria, 2011-02-18)
Oxidative stress is a process characterized by the antioxidant defense system
decrease and/or an excessive reactive species (RS) production. RS are substances
capable of attacking proteins, lipids and DNA. The oxidative ...
Influência do polimorfismo Ala16Val do gene da enzima superóxido dismutase (SOD2) no efeito antioxidante in vitro do citrato de clomifeno
(Universidade Federal de Santa Maria, 2011-08-16)
To investigate the in vitro antioxidant properties of the ovulation induction drug,
Citrate clomiphene (CC), and to access whether its effects are influenced by the
Ala16Val polymorphism in the SOD2 gene, which encodes ...
Avaliação de biomarcadores inflamatórios, oxidativos e vasculares em pacientes com hipercolesterolemia
(Universidade Federal de Santa Maria, 2011-03-21)
Hypercholesterolemia is a determining factor for the development of atherosclerosis, which is
considered the main cause of cardiovascular diseases. In Brazil, as in most developed
countries, cardiovascular diseases are ...
Efeitos do exercício físico sobre parâmetros de estresse oxidativo em ratos hipertensos
(Universidade Federal de Santa Maria, 2011-09-05)
Hypertension has been regarded as one of the most important factors associated with the
development of vascular disease and is closely linked to increased reactive oxygen species (ROS). In
contrast, exercise has been ...
Efeito do extrato de Syzygium cumini, in vitro, na atividade de enzimas que degradam nucleotídeos e nucleosídeos de adenina e ésteres de colina e sobre o perfil oxidativo em pacientes com Diabetes Mellitus tipo 2
(Universidade Federal de Santa Maria, 2011-02-01)
Diabetes mellitus (DM) is a metabolic disorder of multiple etiology characterized by chronic hyperglycemia resulting from deficiency of production and / or insulin action. This state of hyperglycemia may cause a variety ...