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Toxicidade do mercúrio em ratas virgens, gestantes e lactantes: efeito protetor do zinco e da N-acetilcisteína
(Universidade Federal de Santa Maria, 2016-07-15)
Mercury (Hg) is a divalent metal found liquid at room temperature without biological functions and anthropogenically released in industrial, agricultural activities and burning of fossil fuels. Toxic effects caused by ...
Envolvimento do sistema da tiorredoxina nas alterações induzidas pelo chumbo in vitro e in vivo: implicações na toxicidade do chumbo
(Universidade Federal de Santa Maria, 2011-11-30)
Oxidative stress is an important molecular mechanism of lead (Pb) toxicity. The thioredoxin
system (selenoenzyme thioredoxin reductase-TrxR, thioredoxin protein- Trx and NADPH) is essential
for the antioxidant defense ...
Atividade de ectoenzimas do sistema purinérgico e análise de biomarcadores inflamatórios e de estresse oxidativo em pacientes com câncer de pulmão
(Universidade Federal de Santa Maria, 2014-11-13)
Lung cancer has been considered a public health problem since it has become one of the most commonly diagnosed neoplastic diseases and one of the most lethal in the world. This spread of lung cancer in the world population ...
Efeitos do resveratrol, do suco de uva e do vinho tinto nos biomarcadores de estresse oxidativo e na atividade de ectoenzimas em ratos diabéticos
(Universidade Federal de Santa Maria, 2012-11-28)
Diabetes mellitus is a major public health problem throughout the world. The chronic hyperglycemia present in the diabetic state is associated with increase of oxidative stress, which has been appointed to play a central ...
Efeitos metabólicos do consumo da castanha do Brasil (Bertholletia excelsa) em humanos saudáveis
(Universidade Federal de Santa Maria, 2014-02-25)
Brazil nut (Bertholletia excelsa, Lecythidaceae family) is the richest known food in selenium. Its consumption has demonstrated efficient in improving the lipid profile and the plasmatic selenium levels as well as to ...
Ação farmacológica do 3-alquinil selenofeno em modelos de convulsão em ratos jovens
(Universidade Federal de Santa Maria, 2012-03-02)
Seizures have important consequences in terms of mortality and quality of life of the affected population, being a risk factor for the development of cognitive and behavioral abnormalities. Considering the promising ...
Avaliação do potencial antioxidante e antibacteriano de Anacardium microcarpum e sua toxicidade em diferentes modelos biológicos in vitro
(Universidade Federal de Santa Maria, 2015-09-11)
Oxidative stress reflects an imbalance between the systemic manifestation of reactive species and a biological system s ability to readily detoxify the reactive intermediates or to repair the resulting damage. This condition ...
Efeito antinociceptivo, antiinflamatório e antioxidante da Aloe saponaria Haw em modelos de queimadura em ratos
(Universidade Federal de Santa Maria, 2013-12-19)
In Brazil, the plant Aloe saponaria Haw, popularly known as babosa pintadinha , has been empirically used for its potential effect on skin burn injury, there are no scientific data confirming its popular use. Thus, the ...
Toxidez de alumínio em genótipos de Pfaffia glomerata (Spreng.) Pedersen e Pfaffia tuberosa (Spreng.) Hicken
(Universidade Federal de Santa Maria, 2008-02-22)
Al toxicity, especially in acid soils, is a determinant factor of lower productivity for
several cultures and, although some studies have been developed to elucidate this problem,
studies on medicinal plants are extremely ...
Atividade da curcumina livre e nanoencapsulada in vitro e in vivo sobre ratos infectados experimentalmente com Trypanosoma evansi
(Universidade Federal de Santa Maria, 2014-02-25)
The aim of this study was to evaluate the in vitro and in vivo trypanocidal activity of free curcumin (F-C) and curcumin-loaded lipid-core nanocapsules (C-LNCs) against Trypanosoma evansi, as well as its antioxidant activity ...