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Efeitos da suplementação com disseleneto de difenila e do exercício físico de natação na memória de ratos wistar velhos
(Universidade Federal de Santa Maria, 2017-03-03)
Aging occurs at all cellular levels of the body, being defined as a degenerative, progressive
and irreversible process. An important feature of the aging process is the gradual loss of
memory. Given the scarcity of ...
Ação farmacológica do 4,4’-dicloro-difenil disseleneto em modelos de hiperglicemia e obesidade em ratos
(Universidade Federal de Santa Maria, 2017-03-03)
The obesity epidemic is a worldwide public health problem and is considered one of the leading causes of death and disability worldwide. This is because the pathophysiology of this disease is extremely complex and involves ...
Desenvolvimento de nanocápsulas contendo disseleneto de bis (p-metoxifenila): biodistribuição e efeitos em modelos de dor em camundongos
(Universidade Federal de Santa Maria, 2017-08-11)
The chronic pain is a global public health problem and its pharmacological management is still unsatisfactory. The identification of novel molecules to effectively treat chronic pain states remains a major objective in ...
Efeito do guaraná (Paullinia cupana) em parâmetros comportamentais e sistemas purinérgico e colinérgico em modelo de hiperlipidemia
(Universidade Federal de Santa Maria, 2017-08-28)
Hyperlipidemia is a condition associated with cognitive and inflammatory
disorders, with has a high impact on cardiovascular diseases and central nervous
system. Guarana, on the other hand, presents potent anti-inflammatory ...
Efeito preventivo do flavonoide quercetina nos sistemas purinérgico e colinérgico de modelo experimental de hiperlipidemia
(Universidade Federal de Santa Maria, 2017-08-30)
Hyperlipidemia (HL) is characterized by changes in lipid metabolism, being one of the main metabolic disorders. HL is recognized as a risk factor for the development of atherosclerosis, characterized by the presence of ...
Estudo comparativo de β-selenoaminas e disselenetos em modelos hepatotóxico e alternativo
(Universidade Federal de Santa Maria, 2017-08-17)
Organic selenium compounds, Ebselen and diphenyl diselenide (DPDS), possess numerous characteristics such as, antioxidant activity, anti-inflammatory among others. In this regard, new molecules have been produced through ...
Efeitos, percepção de fármacos e comunicação química em peixes
(Universidade Federal de Santa Maria, 2017-06-08)
The presence of drugs in aquatic environments has been studied for decades and their actions have as consequence changes of several physiological mechanisms. It is known that there is a complex chemical communication between ...
Exposição a agroquímicos altera o funcionamento do eixo hipotálamo-hipófise-interrenal em zebrafish
(Universidade Federal de Santa Maria, 2017-08-21)
The increase of human occupation in rural areas and the intensification of agricultural practices produces increasingly agrochemical waste up to aquatic ecosystems. Based on this, many studies are needed to clarify the ...
Contribuições do internato curricular em atenção primária à saúde na evolução de competências por estudantes de graduação em Medicina
(Universidade Federal de Santa Maria, 2017-02-21)
The curricular internship is one of the privileged spaces for learning in medical education. The incorporation of Primary Health Care (PHC) as a mandatory area, with defined workload, is one of the consequences of National ...
A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...