Buscar
Itens para a visualização no momento 1-10 of 26
Disfunção imune em indivíduos HIV positivos sob terapia antirretroviral: papel da razão CD4/CD8 e da atividade da enzima adenosina desaminase
(Universidade Federal de Santa Maria, 2021-03-31)
Human immunodeficiency virus (HIV) uncontrolled replication results in the Acquired
Immunodeficiency Syndrome (AIDS). Antiretroviral therapy (ART) reduces morbidity
and mortality but inflammation and immune activation ...
Fibras musculares oxidativas e glicolíticas apresentam resposta inflamatória e alterações bioenergéticas peculiares após uma contusão musculoesquelética em ratos
(Universidade Federal de Santa Maria, 2021-02-19)
Muscle contusion represents a type of stress that disrupts cell homeostasis. Characterized by traumatic lesion, that impair the availability of oxygen (O2) in the tissue, promotes an increase in the production of reactive ...
Modelagem do fenótipo de diabetes em Nauphoeta cinerea usando estreptozotocina: Foco no metabolismo da glicose no cérebro
(Universidade Federal de Santa Maria, 2021-05-16)
The brain is highly dependent on adequate glucose catabolism, but changes in brain glucose transport are well documented in hyperglycemic conditions. Recent evidence of “hyperglycemic memory" further suggests that chronic ...
Peixes como modelo biológico para o monitoramento ambiental em áreas agrícolas
(Universidade Federal de Santa Maria, 2021-08-31)
The high demand for food has led to a greater number of pesticides used in crops, causing an environmental impact on aquatic environments near these locations. To assess the impacts on aquatic environments, biomonitoring ...
Conservação de crustáceos límnicos: efeito da temperatura e pesticidas no metabolismo oxidativo de Aegla longirostri, in situ e ex-situ
(Universidade Federal de Santa Maria, 2021-08-31)
Freshwater ecosystems, especially low-order streams, are constantly threatened by the advance of agricultural activities that end up contaminating these places with pesticides and degrading the surrounding vegetation, which ...
Envolvimento do receptor de potencial transitório anquirina 1 e efeito farmacológico da diosmetina na queimadura de pele induzida pela radiação UVB em camundongos
(Universidade Federal de Santa Maria, 2021-05-11)
Excessive exposure to type B ultraviolet radiation (UVB) can lead to several changes to the skin resulting from the oxidative and inflammatory processes installed through the neuronal and non-neuronal receptors activation. ...
Fenótipos relacionados à dor em peixe-zebra: uma caracterização neurocomportamental utilizando o modelo de dor visceral induzida pelo ácido acético
(Universidade Federal de Santa Maria, 2021-08-26)
The zebrafish (Danio rerio) is a small freshwater teleost belonging to the Cyprinidae family, which has been studied in different scientific areas. This species has evolutionarily conserved genes and a relatively complex ...
Estudo da disfunção mitocondrial em modelos de doença de Parkinson in vitro e in vivo e perspectivas terapêuticas
(Universidade Federal de Santa Maria, 2021-10-01)
Parkinson disease (PD) is a neurodegenerative disease which symptoms are consequence of progressive neuron lost, especially dopaminergic neurons. Other feature related to PD is mitochondrial dysfunction which could target ...
Efeito neuroprotetor do exercício de natação e do disseleneto de m-trifluormetil difenila em um modelo de dieta hipercalórica em camundongos jovens
(Universidade Federal de Santa Maria, 2021-05-21)
The nutrition transition process has generated negative impacts on population health. The increasing consumption of foods and beverages with higher energy density and lower nutritional value promotes damage to the body, ...
Efeitos do diclofenaco sobre marcadores inflamatórios e de estresse oxidativo em ratos submetidos a consecutivos sets exaustivos
(Universidade Federal de Santa Maria, 2021-07-07)
Physical exercise sessions represent some stress due to the fact that it alters body homeostasis. High oxygen consumption during exercise increases the production of reactive oxygen species (ROS) and pro-inflammatory ...