Centro de Referência de Imunobiológicos Especiais: o que se conhece sobre esse programa?

Abstract

In 1993, the Ministry of Health began gradually implementing the Reference Centers for Special Immunobiologicals (CRIE). CRIE aims to facilitate access to immunobiologicals, especially for immunodeficient people and those with risk conditions. This work aims to develop a literature review study on what CRIE is and what is researched in CRIEs. The method is a literature review through searches in the Pubmed, Scielo and Google Scholar databases, using the following descriptors: Reference Center for Special Immunobiologicals, special immunobiologicals and special vaccines. The CRIE Manual was also used as a data source. Few studies were found that evaluate CRIEs and some studies carried out in CRIEs on the study of vaccines, such as yellow fever and HPV. The studies identified that the most administered vaccine was the 23-valent Pneumococcal vaccine and the clinical conditions of HIV/AIDS, chronic lung disease and type 2 diabetes mellitus are the most frequent. Furthermore, studies indicate that it is necessary to advance in the implementation of CRIEs, requiring greater structuring of them. Greater training is also needed for professionals who supply vaccine systems, given the need for data completeness, essential for evaluating post-vaccination adverse events, which is one of CRIE's responsibilities. Above all, a movement for vaccination is necessary.