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Impactos da carbamilação e da icterícia induzidas in vitro sobre a quantificação de parâmetros laboratoriais associados à coagulação sanguínea
(Universidade Federal de Santa Maria, 2023-01-17)
Hemostasis is a process highly regulated by pro-coagulant and anticoagulant proteins with the
purpose of maintaining blood flow within the vessels and capable of promoting coagulation
when there is vascular damage. Changes ...
Atividade antimicrobiana do óleo essencial de Gaultheria procumbens: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2022-08-14)
The pharmacological study of medicinal plants has been highlighted by the identification of
new substances. Plant secondary metabolites are substances produced in response to stress,
often related to attacks by herbivores, ...
Revisão sistemática e metanálise do efeito analgésico do ácido alfa-lipóico em estudos clínicos e atividade antinociceptiva em um modelo de SDCR tipo I
(Universidade Federal de Santa Maria, 2023-02-10)
Chronic pain is a common type of disabling pain, which may or may not be related to other pathologies. It is known that oxidative stress generates compounds that activate ion channels, which are related to increased pain ...
Perfil clínico, oxidativo e inflamatório em pacientes com SARS-CoV-2
(Universidade Federal de Santa Maria, 2023-02-28)
In December 2019, cases of serious illness that caused an outbreak of pneumonia of unknown
origin were reported in Wuhan, Hubei Province, China. Soon after, the number of cases
skyrocketed dramatically, spreading across ...
Fotoinativação de micobactérias de crescimento rápido por porfirinas tetra-catiônicas
(Universidade Federal de Santa Maria, 2023-01-23)
Antimicrobial Photodynamic Inactivation (aPDI) is an emerging non-invasive treatment that
involves the use of a photosensitizer (PS), light and molecular oxygen to inactivate
microorganisms. Thus, the application of aPDI ...
Análise de modificações proteicas induzidas in vitro sobre a formação de produtos proteicos de oxidação avançada e a quantificação de proteína C-reativa
(Universidade Federal de Santa Maria, 2023-02-24)
Non-enzymatic protein modification reactions occur physiologically and affect many
proteins. In some situations, such as kidney and inflammatory diseases, these
reactions are exacerbated. The consequences of these ...
Hemodiálise: controle de infeção, qualidade microbiológica do líquido de diálise versus reuso de dialisadores
(Universidade Federal de Santa Maria, 2023-01-25)
Introduction: The high incidence of complications originating from venous accesses has
stimulated the development of research based on the environment were hemodialysis sessions.
In this context, the microbiological ...
Determinação de impurezas elementares por espectrometria de absorção atômica em produtos farmacêuticos utilizados por pacientes com doença renal crônica
(Universidade Federal de Santa Maria, 2023-02-02)
Patients with chronic kidney disease (CKD) have the functions of filtering fluids and excreting
impurities from the body compromised. Often, these patients have comorbidities, requiring the
use of various medications ...
Atividades biológicas, isolamento de compostos ativos e caracterização de extratos obtidos de Scutia Buxifolia Reissek.
(Universidade Federal de Santa Maria, 2014-03-20)
Scutia buxifolia Reissek belongs to the Rhamnaceae family and is popularly known as
coronilha. The stem bark infusion is popularly used as cardiotonic, antihypertensive and
diuretic. This work aims to determine the ...
Desenvolvimento e avaliação biológica in vitro de sistemas nanoestruturados contendo um novo organoseleneto: utilização de diferentes abordagens tecnológicas visando a sensibilização de células tumorais resistentes
(Universidade Federal de Santa Maria, 2023-04-28)
Cancer is one of the major causes of mortality worldwide and has become a public health problem. Most of the conventional cancer treatments are nonspecific and do not target the tumor cells only, also affecting healthy ...