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Itens para a visualização no momento 21-30 of 66
Efeito da (+)-catequina sobre adiscinesia orofacial induzida por reserpina em camundongos e atividade damonoaminoxidase
(Universidade Federal de Santa Maria, 2018-03-20)
Tardive dyskinesia (TD) is a disabling and debilitating disorder due to the chronic use of antipsychotics that affects around 20% to 50% of patients. It is characterized by involuntary, repetitive and abnormal movements ...
Efeito toxicogenético do polimorfismo Ala16Val do gene MnSOD em leucócitos expostos in vitro ao metil mercúrio
(Universidade Federal de Santa Maria, 2012-03-19)
The environmental contamination by methyl mercury (MeHg) is a great health public problem in
some world regions like Amazonia. The MeHg toxic effects seem to be influenced by
environmental and genetic factors. However, ...
Efeito da rutina e da curcumina em marcadores inflamatórios e oxidativos em modelo experimental de hiperlipidemia
(Universidade Federal de Santa Maria, 2019-02-28)
Hyperlipidemia is characterized by lipid abnormalities that result in inflammation and
oxidative damage, factors involved in the development of atherosclerosis. Adenosine and
adenosine deaminase (ADA) modulate ...
Respostas bioquímicas e comportamentais de peixe-zebra (Danio rerio) expostos a imidacloprido: avaliação do dano oxidativo e perfil antioxidante
(Universidade Federal de Santa Maria, 2019-03-29)
Pesticides are the biggest polluters of water and soil and can reach non-target organisms such as fish. Indiscriminate application of products has been a serious concern and Brazil is one of the countries that uses the ...
Contribuição do sistema colinérgico e da sinalização do NRF2/HO-1 para a ação anti-amnésica do 7-flúor-1,3- difenilisoquinolina-1-amina em camundongos
(Universidade Federal de Santa Maria, 2019-07-26)
Dementia is a heterogenic condition characterized by different symptoms and theories about its pathogenesis, which results in difficult to understand and in the treatment of this disease. The 7-fluoro-1,3-diphenylisoquin ...
Efeito anti-inflamatório do ácido cafeico sobre o sistema purinérgico e colinérgico em ratos Diabéticos tipo 1
(Universidade Federal de Santa Maria, 2020-02-27)
Diabetes mellitus (DM) is a metabolic disorder, considered one of the biggest public health problems in the world. This disease is characterized by a state of chronic hyperglycemia that leads to metabolic disorders. Studies ...
Atividade antitumoral da berberina em células de neuroblastoma SH-SY5Y
(Universidade Federal de Santa Maria, 2017-02-23)
Neuroblastoma is the most common tumor found in the first year of life and represent 6% of the all childhood cancers. There is few options of treatment and the mortality is close to 21%, or exceeds 50% between the high ...
Associação do disseleneto de difenila e moduladores do sistema glutamatérgico frente ao dano oxidativo causado por ácido quinolínico
(Universidade Federal de Santa Maria, 2013-02-22)
Excessive formation of reactive oxygen species (ROS) and disruption of glutamate
uptake have been hypothesized as key mechanisms contributing to quinolinic acid (QA)-
induced toxicity. Thus, here we investigate if the ...
Atividade de ectoenzimas e de colinesterases e biomarcadores de estresse oxidativo em pacientes com câncer de pulmão
(Universidade Federal de Santa Maria, 2012-03-02)
Lung cancer has become one of the most commonly diagnosed neoplastic diseases, as well as one of the most lethal worldwide, characterized, therefore, as a public health problem. This spread of lung cancer in the world ...
Avaliação da capacidade do disseleneto de difenila em reduzir a falência hepática aguda induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2013-09-18)
Paracetamol (APAP) is commonly used analgesic and antipyretic, however high doses can induce damage hepatic. The metabolic N-acetyl-p-benzoquinone imine (NAPQI) is responsible for the toxic effects. The accumulation of ...