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Nanopartículas contendo propionato de clobetasol: preparação, caracterização e incorporação em hidrogéis
(Universidade Federal de Santa Maria, 2010-03-29)
The aim of this work was the development of nanostructured formulations containing
clobetasol propionate. Initially, it was validated a chromatographic method to assay clobetasol
propionate in nanocapsule suspensions. ...
Análise fitoquímica das raizes e folhas, e morfo-anatômica dos caules e folhas de Urera baccifera Gaudich
(Universidade Federal de Santa Maria, 2012-07-05)
The plant Urera baccifera Gaudich, known as stinging nettle, had its leaves and roots used to urinary infections and arthritis. Studies about its anti-inflammatory activities already exist, but are few the studies about ...
Atividades antibacteriana e antibiofilme do extrato bruto de Datura suaveolens
(Universidade Federal de Santa Maria, 2019-06-15)
Control of infectious microorganisms is sometimes ineffective even with the development of innovative antibacterial drugs. As a result, pathogens are proving resistant to most known drugs impacting the premature death of ...
Efeitos da oxima butano-2,3-dionatiossemicarbazona frente ao dano testicular causado por cádmio em camundongos
(Universidade Federal de Santa Maria, 2014-03-06)
We investigated the action of butane-2,3-dione thiosemicarbazone oxime against the testicular damage caused by cadmium chloride (CdCl2) in mice swiss adult male. The animals received a single injection of CdCl2 at the dose ...
Otimização de nanoemulsões contendo óleo essencial de tomilho: estabilidade, atividade antifúngica e liberação in vitro
(Universidade Federal de Santa Maria, 2019-07-02)
The main objective of this work was the optimization of nanoemulsions containing Thymus vulgaris essential oil (20 mg/mL) obtained from the high speed homogenization method, without the use of organic solvents and high ...
Determinação de benzodiazepínicos em plasma por cromatografia líquida com detector ultravioleta-visível empregando microextração líquido-líquido dispersiva
(Universidade Federal de Santa Maria, 2020-03-27)
Drugs has been the main agents involved in intoxications in Brazil. According to the latest
report of SINITOX, these agents summed up 20367 cases representing 26,79% of all agents
involved. Among them, 9983 cases were ...
Determinação de impurezas elementares em suplementos alimentares por espectrometria de absorção atômica
(Universidade Federal de Santa Maria, 2018-08-02)
This work presents a study of the determination of arsenic, cadmium and lead in food
supplements by atomic absorption spectrometry. Food supplements are obtained in synthetic
form and derived from plants, and contamination ...
Avaliação da atividade fotodinâmica frente a agentes de micoses cutâneas e subcutâneas
(Universidade Federal de Santa Maria, 2018-08-24)
Cutaneous and subcutaneous mycoses affect both immunocompeten individuals and immunocompromised individuals. Generally prolonged therapeutic treatments and, recurrences during treatment are quite common. Scopulariopsis ...
Avaliação de potência/teor de toxina botulínica tipo a por métodos cromatográficos e bioensaios
(Universidade Federal de Santa Maria, 2018-07-24)
The botulinum toxin type A is one of the seven different serotypes of toxins produced by fermentation process with Clostridium botulinum, under anaerobic conditions. Biotechnological product has been used in therapeutic ...
Molécula de dano renal-1 na urina e sua associação com o controle glicêmico e com a concentração urinária das interleucinas 1 e 6 no diabetes tipo 2
(Universidade Federal de Santa Maria, 2018-08-17)
Diabetes kidney disease (DRD) is among the main and most relevant complications of diabetes mellitus (DM). Hyperglycemia and inflammation are two of several factors involved in the development and progression of DM ...