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Epidemiologia e investigação de mecanismos de resistência aos carbapenêmicos e polimixinas em bacilos gram-negativos multirresistentes
(Universidade Federal de Santa Maria, 2018-09-28)
Bacterial resistance is a global public health problem and leads to relapsing nosocomial infections, high morbidity and mortality rates and high financial impact. Carbapenems and polymyxins are extensively antimicrobials ...
Determinação de impurezas elementares em suplementos alimentares por espectrometria de absorção atômica
(Universidade Federal de Santa Maria, 2018-08-02)
This work presents a study of the determination of arsenic, cadmium and lead in food
supplements by atomic absorption spectrometry. Food supplements are obtained in synthetic
form and derived from plants, and contamination ...
Avaliação da atividade fotodinâmica frente a agentes de micoses cutâneas e subcutâneas
(Universidade Federal de Santa Maria, 2018-08-24)
Cutaneous and subcutaneous mycoses affect both immunocompeten individuals and immunocompromised individuals. Generally prolonged therapeutic treatments and, recurrences during treatment are quite common. Scopulariopsis ...
Avaliação de potência/teor de toxina botulínica tipo a por métodos cromatográficos e bioensaios
(Universidade Federal de Santa Maria, 2018-07-24)
The botulinum toxin type A is one of the seven different serotypes of toxins produced by fermentation process with Clostridium botulinum, under anaerobic conditions. Biotechnological product has been used in therapeutic ...
Molécula de dano renal-1 na urina e sua associação com o controle glicêmico e com a concentração urinária das interleucinas 1 e 6 no diabetes tipo 2
(Universidade Federal de Santa Maria, 2018-08-17)
Diabetes kidney disease (DRD) is among the main and most relevant complications of diabetes mellitus (DM). Hyperglycemia and inflammation are two of several factors involved in the development and progression of DM ...
Hidrogel de base nanotecnológica contendo silibinina com ação anti-inflamatória no modelo de óleo de cróton
(Universidade Federal de Santa Maria, 2018-11-30)
Currently, irritant contact dermatitis is the most prevalent dermatitis among the others and is triggered
by the activation of innate immunity after skin contact with irritants. Silibinin (SB), a naturally occurring ...
Atividade do óleo de Cymbopogon flexuosus livre e nanoestruturado frente a micobactérias de crescimento rápido
(Universidade Federal de Santa Maria, 2018-02-28)
Rapidly Growing Mycobacteria (RGM) are emerging pathogens responsible for various
human infections, although they are often considered only as contaminants or colonizers. The
formation of biofilms by these ...
Desenvolvimento de nanocápsulas poliméricas com diferentes revestimentos para a liberação cerebral de vimpocetina
(Universidade Federal de Santa Maria, 2018-02-02)
Vinpocetine (VP) is used in neurodegenerative diseases, and researches have
indicated a promising anticonvulsant effect of this drug. However, it shows some limitations as
low aqueous solubility and short half-life. ...
Avaliação anti-inflamatória e antioxidante do extrato de tucumã (Astrocaryum aculeatum): estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2018-01-19)
With the rise of new concepts such as functional foods, nutraceuticals and phytomedicines, allied to the use of traditional medicine, products of plant origin are in evidence. Brazil is a highlight in the development of ...
Avaliação de parâmetros de estresse oxidativo em gestantes gemelares
(Universidade Federal de Santa Maria, 2018-01-05)
Twin pregnancies are considered to be of high obstetric risk due to several morbidities frequently present due to the increased supply of metabolic compounds to fetuses and the high oxygen consumption by the fetus-placenta ...