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Estudo de toxicidade aguda e subaguda do extrato bruto das cascas de Luehea divaricata Mart. em ratos wistar
(Universidade Federal de Santa Maria, 2015-12-14)
The species Luehea divaricata Martius belongs to the Malvaceae family and is popularly known as "açoita-cavalo." It occurs naturally in northeastern Argentina, eastern Paraguay and northern Uruguay. In Brazil, predominates ...
Avaliação de parâmetros de estresse oxidativo em gestantes gemelares
(Universidade Federal de Santa Maria, 2018-01-05)
Twin pregnancies are considered to be of high obstetric risk due to several morbidities frequently present due to the increased supply of metabolic compounds to fetuses and the high oxygen consumption by the fetus-placenta ...
Controle botânico, físico-químico e atividade anti-inflamatória de Glechon spathulata Benth. (Lamiaceae)
(Universidade Federal de Santa Maria, 2010-07-13)
The quality of plant-derived drugs must be ensured through tests of authenticity (organoleptic features,
macro and microscopic identification), purity and integrity (foreign matter, total ash, acid insoluble ash, loss ...
Suscetibilidade de isolados de Candida dubliniensis sensíveis e resistentes ao fluconazol frente a azólicos e equinocandinas
(Universidade Federal de Santa Maria, 2014-06-10)
Candida spp. is the most common etiologic agent of opportunistic fungal infections and Candida albicans species still remains the most frequently isolated species in candidiasis. However, the rate of Candida non-albicans ...
Metabolismo de nucleotídeos e nucleosídeo da adenina em linfócitos e plaquetas de pacientes com hepatite C
(Universidade Federal de Santa Maria, 2016-07-19)
Hepatitis C is an infectious disease caused by Hepatitis C virus (HCV) and characterized by development of inflammation as well as fibrosis. On the other hand, the extracellular nucleotides and adenine nucleosides are ...
Atividade de enzimas que degradam nucleotídeos e nucleosídeo da adenina em linfócitos de gestantes soropositivas para toxoplasmose
(Universidade Federal de Santa Maria, 2013-06-26)
Toxoplasmosis, caused by the intracellular protozoan Toxoplasma gondii is an infectious disease, and this triggers the activation of the immune system. The pregnancy, in turn, shows characteristics of systemic inflammatory ...
Hidrogéis de goma de alfarroba contendo compostos indólicos nanoencapsulados com ação anti-inflamatória em desordens cutâneas induzidas em camundongos
(Universidade Federal de Santa Maria, 2019-03-29)
The skin is constantly exposed to external stimuli, such as irritants substances and ultraviolet
radiation type B (UVB), which can trigger an inflammatory response. Indole-3-carbinol (I3C)
and 3-3'-diindolmethane (DIM) ...
Desenvolvimento de nanocápsulas poliméricas para liberação pulmonar do dipropionato de beclometasona
(Universidade Federal de Santa Maria, 2013-03-22)
Polymeric nanocapsules have been studied extensively for drug delivery by various routes of administration. Currently, the nanoencapsulation of drugs is considered the most efficient means of ensuring controlled release, ...
Suscetibilidade in vitro de isolados clínicos de Candida glabrata sensíveis e resistentes ao fluconazol frente à combinações entre fármacos antifúngicos e não antifúngicos
(Universidade Federal de Santa Maria, 2013-07-19)
Candida species are the most common etiologic agent of opportunistic fungal infections. Candida albicans is the most frequent species in candidiasis, however species of non-albicans species have emerged increasingly in ...
Desenvolvimento e validação de métodos analíticos para o doseamento de daptomicina injetável
(Universidade Federal de Santa Maria, 2013-08-30)
This work presents the development and validation of analytical methods to assay daptomycin injection. Daptomycin is a drug of a new class of antibiotics, known as cyclic lipopeptides. It was approved in USA in 2003 and ...