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Itens para a visualização no momento 11-20 of 191
Avaliação da atividade fotodinâmica frente a agentes de micoses cutâneas e subcutâneas
(Universidade Federal de Santa Maria, 2018-08-24)
Cutaneous and subcutaneous mycoses affect both immunocompeten individuals and immunocompromised individuals. Generally prolonged therapeutic treatments and, recurrences during treatment are quite common. Scopulariopsis ...
Avaliação de potência/teor de toxina botulínica tipo a por métodos cromatográficos e bioensaios
(Universidade Federal de Santa Maria, 2018-07-24)
The botulinum toxin type A is one of the seven different serotypes of toxins produced by fermentation process with Clostridium botulinum, under anaerobic conditions. Biotechnological product has been used in therapeutic ...
Molécula de dano renal-1 na urina e sua associação com o controle glicêmico e com a concentração urinária das interleucinas 1 e 6 no diabetes tipo 2
(Universidade Federal de Santa Maria, 2018-08-17)
Diabetes kidney disease (DRD) is among the main and most relevant complications of diabetes mellitus (DM). Hyperglycemia and inflammation are two of several factors involved in the development and progression of DM ...
Avaliação da toxicidade do extrato bruto das folhas de Hibiscus rosa-sinensis Linn. e do efeito da radiação gama sobre esse extrato
(Universidade Federal de Santa Maria, 2017-08-18)
Hibiscus rosa-sinensis Linn., plant belonging to the family Malvaceae and popularly known as hibiscus, “mimo-de-vênus” and “hibisco-da-china”, is used in traditional medicine as hair growth promoters, to improve digestion, ...
Desenvolvimento de nanocápsulas para a liberação controlada de crisina: avaliação da atividade antioxidante e da citotoxicidade in vitro
(Universidade Federal de Santa Maria, 2015-09-25)
Chrysin (5,7-dihydroxyflavone) is a flavonoid (class of flavones), which presents antioxidant and antitumoral activities. However, it has low solubility and hence its bioavailability in the body is low, limiting its ...
Desenvolvimento de micropartículas e comprimidos microparticulados contendo piperina
(Universidade Federal de Santa Maria, 2019-08-30)
Piperine is an alkaloid extracted from plants of the Piper genus, among which is the Piper nigrum species, the black pepper, widely employed in Indian cooking and traditional medicine. Moreover, piperine exhibits important ...
Reposicionamento e avaliação da atividade antibacteriana e de clivagem do DNA plasmidial in vitro dos não antibióticos Anlodipino e Valsartana
(Universidade Federal de Santa Maria, 2019-12-19)
Infections caused by multiresistant microrganisms have increased considerably in recent years,
reaching approximately one fifth of worldwide mortality, becoming a public health problem. Another
worrying factor is the ...
Avaliação in vitro da atividade de antimicrobianos na cavidade bucal sobre Candida glabrata sensíveis e resistentes ao fluconazol
(Universidade Federal de Santa Maria, 2016-03-21)
Oropharyngeal candidiasis is a challenging fungal disease in the clinical setting of immunocompromised patients, either by their morbidity or by its difficulties in treatment. Patients with AIDS, cancer, and transplanted ...
Desenvolvimento e validação de métodos cromatográficos para avaliação de teor/potência de insulina glargina
(Universidade Federal de Santa Maria, 2016-03-30)
hans, and is secreted into the bloodstream. It plays and important role in regulating the
metabolic activities of the body, particularly the homeostasis of the blood glucose. Insulin
glargine is a recombinant human insulin ...
Estudo de métodos cromatográficos e ensaio biológico para avaliação do anticorpo monoclonal denosumabe
(Universidade Federal de Santa Maria, 2017-07-27)
Denosumab (DmAb) is a fully human monoclonal antibody that inhibits osteoclast formation, function and survival, reducing bone turnover and resorption. Structurally, it is a fully human immunoglobulin G2, yielding a molecular ...