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Itens para a visualização no momento 21-30 of 43
Envolvimento dos sistemas purinérgico, colinérgico e estresse oxidativo nos distúrbios da tireoide: possível efeito protetor da quercetina
(Universidade Federal de Santa Maria, 2017-02-22)
Thyroid hormones modulate the metabolic pathways in the body and have important physiological
functions in the brain and vascular system. Changes in their production or distribution lead to disorders
such as hypothyroidism ...
Ação farmacológica do 4,4’-dicloro-difenil disseleneto em modelos de hiperglicemia e obesidade em ratos
(Universidade Federal de Santa Maria, 2017-03-03)
The obesity epidemic is a worldwide public health problem and is considered one of the leading causes of death and disability worldwide. This is because the pathophysiology of this disease is extremely complex and involves ...
Dieta suplementada com disseleneto de difenila atenua as alterações bioquímicas e comportamentais no modelo de hipotireoidismo induzido por metimazol
(Universidade Federal de Santa Maria, 2012-12-14)
Hypothyroidism is a syndrome resulting from decreased production and secretion of triiothyronine (T3) and thyroxine (T4) hormones, frequently diagnosed in women. Clinical and experimental evidence support the association ...
Mecanismos de toxicidade de Duguetia furfuraceae A. St.-Hill no modelo de Drosophila melanogaster e avaliação do potencial antifúngico.
(Universidade Federal de Santa Maria, 2015-12-04)
Duguetia furfuracea is a common shrub from Brazilian cerrado areas, known as "ata brava", often used as a medicinal plant especially in treatment of renal colic and rheumatism. However, pharmacological studies with extracts ...
Respostas bioquímicas em carpas (Cyprinus carpio) expostas a duas formulações comerciais de inseticidas em condições de lavoura de arroz e em laboratório
(Universidade Federal de Santa Maria, 2012-07-27)
The pesticides are substances widely used in agriculture, because it enhances productivity. However, its excessive and disordered use has caused different impacts on the environment. Therefore, this study investigated the ...
Silimarina modifica a atividade da Na+/K+-ATPase e da MAO e modula a ação de antimicrobianos in vitro
(Universidade Federal de Santa Maria, 2015-06-10)
The Silymarin is a flavonolignan complex isolated from milk thistle seeds of Silybum marianum being used in the treatment of injury related to oxidative stress, including liver and neurological diseases, as Parkinson ...
Efeitos de compostos orgânicos de selênio frente à toxicidade induzida por glutamato e metilmercúrio
(Universidade Federal de Santa Maria, 2012-03-02)
Organoselenium compounds have been proposed as potential pharmacological agents in the treatment of diseases associated with the oxidative stress. Particularly, ebselen and diphenyl diselenide has been demonstrated as ...
Efeitos da N-acetilcisteína sobre a toxicidade do ditelureto de difenila no encéfalo de camundongos
(Universidade Federal de Santa Maria, 2015-11-18)
The diphenyl ditelluride (PhTe)2 is one of the most toxic organic compounds of tellurium which can make their use unsafe. The mechanism(s) involved in (PhTe)2 toxicity is(are) elusive, but thiol oxidation of critical ...
Estudo do perfil oxidativo e avaliação de parâmetros enzimáticos em pacientes com câncer de próstata
(Universidade Federal de Santa Maria, 2012-12-19)
Prostate cancer is recognized as one of the most important medical problems in
the male population. Inherent or acquired alterations in cellular metabolism that occur
over the years may be involved in the process of ...
Efeitos de compostos orgânicos de selênio na toxicidade induzida por metilmercúrio: estudos in vitro
(Universidade Federal de Santa Maria, 2014-10-23)
Methylmercury (MeHg) is a known environmental pollutant that affects a variety of cellular functions, and the
oxidative stress is one of the proposed mechanisms to explain its toxicity. Inhibition of selenoenzymes
(Glutathione ...