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Atividade de ectoenzimas do sistema purinérgico e análise de biomarcadores inflamatórios e de estresse oxidativo em pacientes com câncer de pulmão
(Universidade Federal de Santa Maria, 2014-11-13)
Lung cancer has been considered a public health problem since it has become one of the most commonly diagnosed neoplastic diseases and one of the most lethal in the world. This spread of lung cancer in the world population ...
Avaliação anatomopatológica de fígado, rim, pulmão e cérebro de camundongos expostos ao composto ditelureto de difenila
(Universidade Federal de Santa Maria, 2014-08-29)
Diphenyl ditelluride (PhTe)2 is an organic tellurium compound widely used as an intermediate in organic synthesis reactions and in the industry. Several studies have shown that this compound causes various toxic effects ...
Efeitos metabólicos do consumo da castanha do Brasil (Bertholletia excelsa) em humanos saudáveis
(Universidade Federal de Santa Maria, 2014-02-25)
Brazil nut (Bertholletia excelsa, Lecythidaceae family) is the richest known food in selenium. Its consumption has demonstrated efficient in improving the lipid profile and the plasmatic selenium levels as well as to ...
Efeitos do exercício físico sobre a atividade de enzimas dos sistemas purinérgico e colinérgico em sangue de ratos hipertensos
(Universidade Federal de Santa Maria, 2014-08-29)
Hypertension is a multifactor clinical condition, which is accompanied by a low-grade
inflammation and alterations in platelet function. These modifications may be related to an
imbalance in the regulation of adenine ...
Efeito antinociceptivo da N-acetilcisteina e da vitamina E em modelos de nocicepção em roedores
(Universidade Federal de Santa Maria, 2014-05-08)
Recently, oxidative stress was indicated as modulator of nociceptive transmission at spinal cord, and that nitric oxide (NO) may activate the TRPV1 in vitro. As no protein thiol compounds (SH) are the main endogenous ...
Efeitos de compostos orgânicos de selênio na toxicidade induzida por metilmercúrio: estudos in vitro
(Universidade Federal de Santa Maria, 2014-10-23)
Methylmercury (MeHg) is a known environmental pollutant that affects a variety of cellular functions, and the
oxidative stress is one of the proposed mechanisms to explain its toxicity. Inhibition of selenoenzymes
(Glutathione ...
Papel do receptor B1 para cininas e o efeito da inibição da enzima conversora de angiotensina em ataques agudos de gota em roedores
(Universidade Federal de Santa Maria, 2014-08-20)
Gout, or gouty arthritis, has been associated of a range of comorbidities as hypertension and kidney diseases. Some studies have indicated that certain antihypertensive drugs, such as angiotensin I-converting enzyme ...
3-(4-Fluorofenilselenil)-2,5 difenilselenofeno produz ação do tipo-antidepressiva em diferentes modelos de depressão em camundongos
(Universidade Federal de Santa Maria, 2014-03-11)
Selenophenes are a promising class of heterocyclic selenium-containing compounds
presenting important pharmacological properties. Based on selenium well-described role on
mood regulation and since depression is a serious ...
Avaliação de marcadores bioquímicos, de estresse oxidativo e do efeito antioxidante da quercetina no hipotireoidismo
(Universidade Federal de Santa Maria, 2014-03-28)
Hypothyroidism is characterized by a disorder resulting from deficiency of
thyroid hormones and is related to lipid metabolism dysfunction and cardiovascular
diseases development risk. However, these changes in hypothyroidism ...
Ação preventiva do cobre sobre alterações bioquímicas e comportamentais induzidas pelo mercúrio em ratos jovens
(Universidade Federal de Santa Maria, 2014-05-30)
This work examined the effectiveness of Cu pre-exposition on biochemical and behavioral changes induced by Hg exposure in young rats treated subcutaneously with saline or CuCl2.2H2O (Cu 2.6 mg/kg/day) from 3 to 7 days old ...