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Dano ao DNA no diabetes tipo 2 e sua associação com inflamação, estresse oxidativo, disfunção endotelial, resistência à insulina e à ocorrência de complicações crônicas microvasculares
(Universidade Federal de Santa Maria, 2016-03-15)
Several pathophysiological mechanisms are associated with type 2 diabetes mellitus (type 2 DM), such as glucotoxicity, insulin resistance, inflammation, oxidative stress and endothelial dysfunction, which can result in DNA ...
Determinação de HPAs presentes na nutrição parenteral e avaliação da exposição de neonatos através da presença do 1-hidroxipireno na urina
(Universidade Federal de Santa Maria, 2016-10-19)
Carbon black, which has polycyclic aromatic hydrocarbons (PAHs) adsorbed
on its surface, is used in the composition of rubber for pharmaceutical used in
injectable drugs and parenteral formulations such as amino acid ...
Caracterização molecular de Echinococcus spp. em bovinos no Rio Grande do Sul e avaliação in vitro e ex vivo do óleo de Melaleuca alternifolia frente aos protoescóleces de Echinococcus ortleppi
(Universidade Federal de Santa Maria, 2016-03-04)
Cystic echinococcosis (CE) is a zoonotic disease caused by Echinococcus genus. The larval stage (hydatid cyst) of the parasite causes serious public health problems, and affects various species of animals, causing economic ...
Estudo etnofarmacológico, fitoquímico e biológico de Poikilacanthus glandulosus (Nees) Ariza
(Universidade Federal de Santa Maria, 2016-08-25)
Poikilacanthus glandulosus is a subshrub distributed in Southeast and South of Brazil, Paraguay, Argentina and Uruguay and belongs to Acathaceae family. The aim of this study was to perform a phytochemical study and ...
Candida parapsilosis: resistência as equinocandinas e a suscetibilidade a antifúngicos isolados e em combinação
(Universidade Federal de Santa Maria, 2016-08-05)
Candida parapsilosis is a yeast fungus that causes a wide spectrum of infections
predominantly in immunocompromised patients and representing a major cause of
infections related to health care. The emergence of resistance ...
Teor de minerais, perfil oxidativo e toxicidade de Nopalea cochenillifera (L.) salm-dick (cactaceae)
(Universidade Federal de Santa Maria, 2016-08-15)
Nopalea cochenillifera (L.) Salm-Dyck occurs from Mexico to Panama and is acclimatized in several countries. It is a shrubby plant that reaches 3-4 m tall, has a cylindrical body and items called cladodes. This species is ...
Extração, identificação e potencialidades farmacêuticas de compostos obtidos da fibra prensada da palma (Elaeis guineensis Jacq.)
(Universidade Federal de Santa Maria, 2016-07-26)
The increase in palm oil demand in the world market generates a greater amount of co-products
resulting from the extraction process. These by-products are being investigated for the presence of
bioactive compounds, since ...
Análise fitoquímica, bromatológica, genotóxica e antimicrobiana de tubérculos de Tropaeolum pentaphyllum LAM
(Universidade Federal de Santa Maria, 2016-08-03)
Tropaeolum pentaphyllum Lam., belonging to Tropaeolaceae family, possess tubers commonly known as ‘’crem’’, popularly used in South of Brazil to the treatment of dermatosis and as spice. In order to verify its properties ...
Caracterização molecular e prospecção de combinações antifúngicas sinérgicas “in vitro” frente a Trichosporon asahii, antes e após exposição prolongada ao fluconazol
(Universidade Federal de Santa Maria, 2016-11-17)
The occurence of invasive fungal infections caused by emerging fungal pathogens has increased considerably in the last decades. The genus Trichosporon comprises species relevant in this context, due to reduced susceptibility ...
Estudo da adulteração com fármacos de suplementos alimentares para emagrecimento e avaliação in silico da interação fármaco-alimento entre sibutramina e grapefruit
(Universidade Federal de Santa Maria, 2016-08-22)
Dietary supplements are considered safe products for consumption because many of them are
from natural source. The consumption of these products has increased as an alternative in the
prevention and treatment of several ...