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Influência do polimorfismo genético Val16Ala-SOD2 e da matriz química do guaraná no estado oxidativo-inflamatório in vitro do cloridrato de ziprasidona
(Universidade Federal de Santa Maria, 2019-03-12)
Antipsychotics (APs) are used to treat schizophrenia and other psychiatric disorders. Most of these
medications have adverse effects causing obesity and metabolic changes associated with oxidative
stress ...
A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...
Efeito antioxidante e imunomodulador de um multissuplemento à base de guaraná, selênio e L-carnitina em modelos in vitro, in vivo e em pacientes com esclerose múltipla
(Universidade Federal de Santa Maria, 2022-08-19)
Multiple sclerosis (MS) is an autoimmune, demyelinating, and neurodegenerative disease, which has neuroinflammation and oxidative stress as key parts of its pathogenesis. Among the clinical forms of the disease, is ...
Impacto toxicogenômico do bisfenol A em diferentes modelos experimentais e potencial efeito reversor de um multisuplemento alimentar
(Universidade Federal de Santa Maria, 2024-05-15)
Introduction: Bisphenol A (BPA) is a synthetic monomer widely used in the plastics industry. Considered an environmental pollutant, it acts as an endocrine disruptor. Its free forms in the body are associated with the ...