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Potencial antiaterogênico da bixina in vivo e in vitro
(Universidade Federal de Santa Maria, 2016-08-25)
Atherosclerosis is a chronic disease characterized by the accumulation of lipids and fibrous elements in the
intima layer of medium and large caliber arteries. Inflammation, oxidative stress as well as low density
lipoprotein ...
Efeito da atorvastatina sobre as alterações comportamentais, histológicas e bioquímicas em camundongos C57BL/6 com status epilepticus induzido por pilocarpina
(Universidade Federal de Santa Maria, 2017-03-06)
Epilepsy is a chronic neurological disease that affects 65 million people worldwide. Temporal
lobe epilepsy (TLE) is the most common type of focal epilepsy in adults, and also the one
with the highest refractoriness index ...
Investigação dos mecanismos associados ao efeito cicatrizante e regenerativo do barbatimão (Stryphnodendron adstringens) em modelos celulares in vitro
(Universidade Federal de Santa Maria, 2019-03-11)
Introduction: The skin is the largest organ of the human body and has the functions of coat, delimitate, protec and interact with the external environment. Skin lesions affect the general population, regardless of gender, ...
A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...
Influência de fatores farmacológicos e nutricionais na resposta oxidativa-inflamatória in vitro induzida pela olanzapina
(Universidade Federal de Santa Maria, 2019-03-13)
Introduction: Olanzapine (OLZ) is a second generation antipsychotic (ASG) used in the treatment of
schizophrenia, bipolar disorder and other neuropsychiatric conditions. The adverse effects of ASG
include ...
Efeito do extrato de Syzygium cumini e alterações provocadas pela síndrome metabólica sobre parâmetros bioquímicos e inflamatórios
(Universidade Federal de Santa Maria, 2013-12-04)
Metabolic syndrome (MetS) is a complex disorder represented by a set of cardiovascular risk factors, including endothelial dysfunction, oxidative stress and inflammation. Syzygium cumini has hypoglycemic, anti-inflammatory, ...
Formação de produtos proteicos de oxidação avançada a partir da reação de fenton e colágeno: efeitos sobre processos inflamatórios em neutrófilos e células renais embrionárias
(Universidade Federal de Santa Maria, 2016-07-05)
The advanced oxidation protein products (AOPPs) are a new class of compounds identified as markers of oxidative damage to proteins. The physiology role of these products is not limited to assess the oxidative stress, and ...
Papel do receptor TRPV1 em um modelo articular de gota aguda em ratos
(Universidade Federal de Santa Maria, 2014-02-17)
The gout is an extremely painful type of arthritis. Despite the large number of drugs available for its treatment, they usually cause many adverse effects that limit their use. Then, further investigations are necessary ...