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Consequências da modulação farmacológica da Na+, K+ - ATPase na epilepsia induzida por pilocarpina
(Universidade Federal de Santa Maria, 2018-08-24)
Epilepsy is one of the most common chronic neurological diseases worldwide, and despite a variety of drugs introduced into clinical practice, one-third of patients remain unresponsive to therapies. In addition, when ...
Caracterização química e avaliação das atividades antimicrobiana, antinociceptiva e anti-inflamatória do própolis da Melipona quadrifasciata quadrifasciata
(Universidade Federal de Santa Maria, 2018-05-10)
The demand for natural products with biological application has become of great interest of
the scientific community and is not different from the products produced by the bees: honey,
propolis, wax and pollen. Several ...
Nanotecnologia potencializa a ação tripanocida do nerolidol em camundongos infectados com Trypanosoma evansi: envolvimento da barreira hematoencefálica
(Universidade Federal de Santa Maria, 2018-11-19)
In spite of significant advances in the studies against Trypanosoma evansi, the effective elimination of protozoan from the central nervous system (CNS) remains a difficult task. The incapacity of trypanocidal drugs ...
Efeito antibacteriano do óleo essencial de Origanum majorana e de compostos isolados na forma pura e nano encapsulada contra à Aeromonas hydrophila em Rhamdia quelen
(Universidade Federal de Santa Maria, 2018-12-07)
The first article aimed to provide a review of the in vivo and in vitro studies that addressed the use of essential oils (EOs) and their main compounds as antimicrobial agents in fish, to identify the best EOs and compounds, ...
Efeitos de inibidores da enzima COX-2 sobre o desenvolvimento de crises convulsivas em camundongos
(Universidade Federal de Santa Maria, 2018-01-12)
Cyclooxygenase-2 (COX-2) inhibitors reduce the synthesis of prostaglandins (PGs) and play an important role in inflammation. In the last decades, research has been focused on the use of COX-2 inhibitors and the inflammatory ...
Interação entre o brometo de piridostigmina e o desbalanço superóxido-peróxido de hidrogênio na cito-genotoxicidade de células neurais e imunes mononucleares
(Universidade Federal de Santa Maria, 2018-06-11)
Pyridostigmine bromide (PB) is a reversible acetylcholinesterase inhibitor (AChE), and the first line of
symptoms associated with neuromuscular junction disorders (JNM) and has been used prophylactically
in the Persian ...
Suscetibilidade in vitro a antifúngicos, frações de óleos essenciais e modelo experimental de infecção por Malassezia pachydermatis
(Universidade Federal de Santa Maria, 2018-07-19)
Malassezia pachydermatis is a zoophilic yeast mainly found in the auditory canal of various animal species, and may also be isolated from the skin of humans. Azole and polyene antifungals are the treatment of choice for ...
Nanoemulsões de Lavandula dentata e de Myristica fragrans: desenvolvimento, estudo de estabilidade e efeito inseticida
(Universidade Federal de Santa Maria, 2018-12-14)
Essential oils have been widely studied in relation to insecticidal activity as an alternative to
conventional insecticides, since the widespread of synthetic compounds has caused damage to
health and environment, as ...
Efeito protetor da quercetina sobre a toxicidade induzida pela oxitetraciclina em Rhamdia quelen
(Universidade Federal de Santa Maria, 2018-08-10)
The culture conditions in the fish culture can lead to stress situations, contributing to the occurrence of infectious
diseases, considered a great challenge for the productive success of this activity. Thus, ...
Atividade de sesquiterpenoides isolados de Nectandra grandiflora Nees sobre o sistema nervoso central
(Universidade Federal de Santa Maria, 2018-12-17)
Nectandra grandiflora (Lauraceae) is a native species from Rio Grande do Sul, Brazil, whose essential
oil (EO) is rich in sesquiterpenoids, such as, (+)-dehydrofukinone (DHF), (-)-selin-11-en-4-alpha-ol (SEL), and
the ...