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Itens para a visualização no momento 41-50 of 67
Caracterização da nocicepção em um modelo de dor do câncer de mama e avaliação da participação do receptor TRPA1 neste modelo em camundongos fêmeas
(Universidade Federal de Santa Maria, 2021-08-27)
Breast cancer can cause bone metastasis, contributing to patients' pain. There is still a portion of patients with breast cancer who have inadequate treatment for pain. The mechanisms associated with cancer pain are still ...
Influência do sexo nas diferenças comportamentais promovidas pela exposição ao etanol em peixes-zebra submetidos à interação com um objeto não familiar
(Universidade Federal de Santa Maria, 2021-12-16)
In humans, ethanol (EtOH) modulates behavioral functions in a biphasic manner, ranging from disinhibition to sedation. The effects of EtOH are dose-dependent and influenced by environmental and individual factors, such as ...
Efeito neuroprotetor do JM-20 em ratos submetidos a traumatismo cranioencefálico leve
(Universidade Federal de Santa Maria, 2021-09-10)
Traumatic brain injury (TBI) is a multisystemic pathology with interactions between central nervous system, peripheral nervous system and immune system. It is one of the main causes of death and desability worldwide. The ...
Influência do sistema adrenérgico na enzima Na+, K+- ATPase no aparecimento de fadiga em córtex de ratos
(Universidade Federal de Santa Maria, 2021-10-07)
Physical exercise brings health benefits, such as reducing neurological diseases and improving the immune system. Although exercise brings such benefits, it is also a stressor for the body, and may impact the immune and ...
Caracterização enzimática da e-ntpdase em linfócitos residentes de orgãos imunes primários, secundários e não imunes de ratos wistar
(Universidade Federal de Santa Maria, 2021-09-03)
Ectoenzymes play an important role in controlling the signaling developed by adenine nucleotides and nucleosides in countless cells. However, little information is found in the scientific literature about the biochemical ...
Efeitos do glifosato sobre o desenvolvimento embrionário, larval e adulto do peixe-zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2021-09-16)
Glyphosate-Based Herbicides (GBH) are the most used pesticides in the world and pose risks to environmental health and to non-target organisms. This work aimed to verify the toxicity, the mechanisms involved and the ...
Mecanismos neurológicos e sistêmicos envolvidos na patogênese da listeriose e impactos do uso de curcumina livre e nanoencapsulada na infecção in vivo
(Universidade Federal de Santa Maria, 2021-10-27)
Foodborne zoonotic disease, listeriosis contains numerous gaps in knowledge regarding its pathogenic mechanisms. In addition, the problem of bacterial resistance requires potential alternatives to treatment. The aim of ...
Modulação dopaminérgica e glutamatérgica na recaída por morfina em ratos: influência da dieta e de fármacos nanoparticulados
(Universidade Federal de Santa Maria, 2021-09-30)
Morphine, in addition to being an analgesic drug, also has a high additive potential related to neuroadaptations of the dopaminergic and glutamatergic pathways, in addition to the increase in oxidative events in the ...
Efeitos benéficos do ácido rosmarínico em modelos de atividade epileptiforme in vivo e in vitro induzidos por pilocarpina
(Universidade Federal de Santa Maria, 2021-12-17)
Epilepsy is a chronic neurological condition marked by the occurrence of epileptic seizures that cause enormous damage to the quality of life of affected patients. Thus, understanding the molecular bases responsible for ...
Avaliação dos efeitos do consumo de uma dieta rica em sacarose em Drosophila melanogaster: ênfase em alterações metabólicas e transcricionais
(Universidade Federal de Santa Maria, 2021-11-09)
The prevalence of diabetes mellitus (DM) has increased in the last decades, with 90% of cases been of type-2 diabetes (T2D), which is characterized by insulin resistance. In addition to hyperglycemia, T2D is strongly ...