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Efeitos do difenil disseleneto sobre a disfunção mitocondrial na insuficiência hepática aguda induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2015-02-26)
Acute liver failure (ALF) induced by acetaminophen (APAP) is a complex process associated
with glutathione (GSH) depletion, energetics metabolism changes and mitochondrial dysfunction,
resulting in the impairment of ...
Efeitos do treinamento aeróbico no processo inflamatório e estresse oxidativo no córtex e músculo e a sua relação com exercícios à exaustão, bem como as adaptações causadas pelo treinamento aeróbico no fígado de ratos
(Universidade Federal de Santa Maria, 2015-01-08)
The regular practice of physical exercise is linked to a good life quality. However, each
physical bout has consequences named reactive oxygen species (ROS) production, low-grade
inflammation, delayed onset muscle soreness ...
Ação da Phα1β, peptídeo purificado do veneno da aranha Phoneutria nigriventer, sobre os efeitos analgésicos e adversos causados pela morfina em camundongos
(Universidade Federal de Santa Maria, 2015-06-19)
Opioids are the most common drugs prescribed worldwide for alleviating moderate to
severe pain. However, the use of opioids is associated with the development of
tolerance to the analgesic effect and potential adverse ...
Efeitos da exposição ao cloreto de mercúrio durante a gestação e lactação em ratas wistar e sua prole: parâmetros bioquímicos e distribuição de mercúrio
(Universidade Federal de Santa Maria, 2015-05-08)
The objective of this work was to evaluate the effects of HgCl2 exposure in drinking
water in pregnant and/or lactating rats and their offspring. Still, it evaluated if the HgCl2
intravenous exposure as well as the renal ...
Efeito farmacológico do disseleneto de m-trifluormetil-fenila na comorbidade entre dor e depressão em camundongos
(Universidade Federal de Santa Maria, 2015-07-24)
Chronic pain and depression often coexist, and several mechanisms are involved in the pathogenesis of this comorbidity, which confer it resistance to treatment. The serotonergic system is considered a central mechanism in ...
Efeito in vitro do extrato de Solanum sessiliflorum: atividade antioxidante e antitumoral (MCF-7 e HT29)
(Universidade Federal de Santa Maria, 2015-11-05)
Epidemiological studies have suggested that intake of fruits and vegetables act in the prevention of several diseases such as cancer and cardiovascular diseases. This can be explained by these bioactive compounds are present ...
Efeitos biológicos do óleo essencial e do extrato hidro alcóolico das folhas de Psidium guajava var. pomifera L.
(Universidade Federal de Santa Maria, 2015-12-17)
The Myrtaceae family has 145 genera. In Brazil are recorded 23 genera and about 1,013 species. Several plants of this family are used in food stuffs, for example, Psidium guajava L. fruits, commonly known as guava. In folk ...
Avaliação do potencial antioxidante e antibacteriano de Anacardium microcarpum e sua toxicidade em diferentes modelos biológicos in vitro
(Universidade Federal de Santa Maria, 2015-09-11)
Oxidative stress reflects an imbalance between the systemic manifestation of reactive species and a biological system s ability to readily detoxify the reactive intermediates or to repair the resulting damage. This condition ...
Diversidade de anfíbios anuros em campos de altitute dos estados de Santa Catarina e Paraná
(Universidade Federal de Santa Maria, 2015-02-27)
Threats to biodiversity in countryside areas are growing in an accelerated rhythm. Researches aiming biodiversity inventory and habitat requirements in these areas are necessary in the pursuit of public policies for the ...
Efeito protetor do extrato de lingonberry sobre o sistema purinérgico e estresse oxidativos no sistema nervoso de ratos diabéticos
(Universidade Federal de Santa Maria, 2015-10-23)
Diabetes mellitus (DM) is considered a metabolic disorder that affects large part of worldwide. The hyperglycemia of diabetes cause cognitive impairments associated with physiological and structural changes in the central ...