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Fenótipos envolvidos em comorbidades associadas às crises convulsivas: abordagens experimentais utilizando o peixe-zebra como organismo modelo
(Universidade Federal de Santa Maria, 2021-02-26)
Epilepsy is a neurological disease characterized by recurrent seizures that affects the cerebral homeostasis. This disease can generate negative consequences for the patient, such as behavioral and cognitive changes. ...
Alterações comportamentais mediadas pelo etanol em peixe-zebra: influência do estresse oxidativo, disfunção mitocondrial e modulação serotoninérgica
(Universidade Federal de Santa Maria, 2020-07-24)
Ethanol consumption is a serious public health problem due to the negative impacts that affect individuals and society. Because the mechanism of action of ethanol in the central nervous system is complex and not fully ...
Agressividade e ansiedade induzidas pelo estresse em peixe-zebra: envolvimento da monoamina oxidase, modulação redox e alterações neuroendócrinas
(Universidade Federal de Santa Maria, 2020-07-24)
Mental disorders are considered XXI century pandemics that cause various health diseases. About a third of people have problems related to mental health worldwide. Furthermore, several disorders are triggered by exacerbated ...
Fenótipos relacionados à dor em peixe-zebra: uma caracterização neurocomportamental utilizando o modelo de dor visceral induzida pelo ácido acético
(Universidade Federal de Santa Maria, 2021-08-26)
The zebrafish (Danio rerio) is a small freshwater teleost belonging to the Cyprinidae family, which has been studied in different scientific areas. This species has evolutionarily conserved genes and a relatively complex ...
Efeitos da taurina na exposição repetida ao etanol em peixe-zebra: parâmetros comportamentais e atividade da monoamina oxidase cerebral
(Universidade Federal de Santa Maria, 2021-07-27)
Alcohol abuse is associated with negative health impacts including high mortality and morbidity rates, as well as induces several behavioral changes. However, drugs available to treat disorders related to alcohol use have ...
Efeitos do glifosato sobre o desenvolvimento embrionário, larval e adulto do peixe-zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2021-09-16)
Glyphosate-Based Herbicides (GBH) are the most used pesticides in the world and pose risks to environmental health and to non-target organisms. This work aimed to verify the toxicity, the mechanisms involved and the ...
Análise do comportamento social do peixe-zebra: uma abordagem sobre respostas do tipo ansiedade e nocifensivas
(Universidade Federal de Santa Maria, 2022-04-28)
Social behavior plays a key adaptative role in several species on animal kingdom. Due to the biological role of this behavior, the use of social animal, such as the zebrafish (Danio rerio), represents a strategy to understand ...
Impactos neuroendócrinos e comportamentais de um inseticida à base de imidacloprid em zebrafish
(Universidade Federal de Santa Maria, 2022-09-16)
Zebrafish is a well-established model organism for translational and ecotoxicological research. Despite having the genome completely sequenced and the behavior and physiology well reported, there are some issues related ...
Efeitos comportamentais e endócrinos da exposição na fase embrionária ao etonogestrel em peixe-zebra
(Universidade Federal de Santa Maria, 2023-09-18)
Improper disposal of expired drugs directly into the garbage or sewage systems
without specific treatment increases concentration of these components in wastewater.
Waste from pharmaceutical industries, used in research ...
Consequências da exposição ao levonorgestrel em zebrafish: efeitos persistentes e transgeracionais
(Universidade Federal de Santa Maria, 2023-09-18)
The consumption of contraceptive medications such as levonorgestrel (LNG) has
increased considerably in recent decades, and consequently its disposal in the
environment, and it has already been detected in different ...