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Itens para a visualização no momento 101-110 of 206
Efeitos de compostos orgânicos de selênio frente à toxicidade induzida por glutamato e metilmercúrio
(Universidade Federal de Santa Maria, 2012-03-02)
Organoselenium compounds have been proposed as potential pharmacological agents in the treatment of diseases associated with the oxidative stress. Particularly, ebselen and diphenyl diselenide has been demonstrated as ...
Efeitos da N-acetilcisteína sobre a toxicidade do ditelureto de difenila no encéfalo de camundongos
(Universidade Federal de Santa Maria, 2015-11-18)
The diphenyl ditelluride (PhTe)2 is one of the most toxic organic compounds of tellurium which can make their use unsafe. The mechanism(s) involved in (PhTe)2 toxicity is(are) elusive, but thiol oxidation of critical ...
Efeitos da N-acetilcisteína sobre o dano oxidativo renal e hepático de ratos diabéticos
(Universidade Federal de Santa Maria, 2010-10-22)
Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia, which is related to oxidative stress and plays an important role in the development of other diseases and tissue damage, such as liver and kidney ...
O papel da enzima Na+,K+-ATPase no déficit cognitivo e no efeito profilático induzido pelo exercício físico após o traumatismo crânio-encefálico
(Universidade Federal de Santa Maria, 2009-09-17)
Traumatic Brain Injury (TBI) is the major cause of death or cognitive deficits in industrialized countries. Although studies have indicate that the oxidative stress and functional deficits after TBI are connected events, ...
Envolvimento do receptor de potencial transitório anquirina 1 e efeito farmacológico da diosmetina na queimadura de pele induzida pela radiação UVB em camundongos
(Universidade Federal de Santa Maria, 2021-05-11)
Excessive exposure to type B ultraviolet radiation (UVB) can lead to several changes to the skin resulting from the oxidative and inflammatory processes installed through the neuronal and non-neuronal receptors activation. ...
Efeito neuroprotetor do exercício de natação e do disseleneto de m-trifluormetil difenila em um modelo de dieta hipercalórica em camundongos jovens
(Universidade Federal de Santa Maria, 2021-05-21)
The nutrition transition process has generated negative impacts on population health. The increasing consumption of foods and beverages with higher energy density and lower nutritional value promotes damage to the body, ...
Estudo do perfil oxidativo e avaliação de parâmetros enzimáticos em pacientes com câncer de próstata
(Universidade Federal de Santa Maria, 2012-12-19)
Prostate cancer is recognized as one of the most important medical problems in
the male population. Inherent or acquired alterations in cellular metabolism that occur
over the years may be involved in the process of ...
Avaliação da capacidade do disseleneto de difenila em reduzir a falência hepática aguda induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2013-09-18)
Paracetamol (APAP) is commonly used analgesic and antipyretic, however high doses can induce damage hepatic. The metabolic N-acetyl-p-benzoquinone imine (NAPQI) is responsible for the toxic effects. The accumulation of ...
Estudo da relação entre os níveis de indicadores biológicos de exposição ao tolueno e o estresse oxidativo em expostos ocupacionalmente a tintas
(Universidade Federal de Santa Maria, 2010-03-19)
Paints occupational exposure is an important health problem due to the wide variety of chemicals and xenobiotics present in their constitution. Organic solvents and heavy metals
are among the main chemical constituents ...
Investigação pós-tratamento agudo e crônico com adenosina exógena no nematoide Caenorhabditis elegans
(Universidade Federal de Santa Maria, 2021-06-25)
Adenosine is a purine, which has important biological functions for cell metabolism, in addition to many researches relating its use to neuromodulation. Caenorhabditis elegans is a non-parasitic nematode found in nature ...