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O papel da enzima Na+,K+-ATPase no déficit cognitivo e no efeito profilático induzido pelo exercício físico após o traumatismo crânio-encefálico
(Universidade Federal de Santa Maria, 2009-09-17)
Traumatic Brain Injury (TBI) is the major cause of death or cognitive deficits in industrialized countries. Although studies have indicate that the oxidative stress and functional deficits after TBI are connected events, ...
Estudo da diversidade de borboletas (Lepidoptera: Rhopalocera) em duas localidades no município de Frederico Westphalen, Rio Grande do Sul, Brasil
(Universidade Federal de Santa Maria, 2007-03-22)
Contributing to the butterflies diversity knowledge from Estacional Decidual Forest of Rio Grande do Sul State, a systematic survey was carried out in two localities of the Municipal District of Frederico Westphalen: Villa ...
Efeito dos carotenóides licopeno e astaxantina sobre danos renais induzidos por cloreto de mercúrio
(Universidade Federal de Santa Maria, 2007-03-09)
Mercury is a heavy metal toxic for any living tissue, being kidneys the first target for the inorganic form. Oxidative stress has been pointed as an important molecular mechanism for kidney injury in inorganic mercury ...
Efeitos do chumbo sobre a atividade da tioredoxina redutase citosólica (TrxR1) e parâmetros de estresse oxidativo em rins de ratos
(Universidade Federal de Santa Maria, 2007-01-31)
Lead is a heavy metal that accumulates primarily in kidney, where exerts its nephrotoxic effects. Several studies suggest that the oxidative stress is an important molecular mechanism for the toxic effects of lead in kidney ...
Efeito inibitório do Ebselen, do disseleneto de difenila e do ditelureto de difenila sobre a atividade da LDH de mamíferos
(Universidade Federal de Santa Maria, 2009-02-09)
Ebselen is a seleno compound whose antioxidant properties have been
attributed to its thiol-peroxidase and thioredoxin-like activity: it decomposes
peroxides at the expense of reduced thiols. However, the excessive ...
Enzimas que hidrolisam nucleotídeos de adenina em plaquetas, agregação plaquetária e polimorfismo do gene α2 da integrina α2β1 em pacientes com a doença de von Willebrand
(Universidade Federal de Santa Maria, 2009-04-08)
Von Willebrand disease (vWD) is one of the most common inherited bleeding diseases, caused by a qualitative or quantitative deficiency of the von Willebrand factor (vWF). vWF is a multimeric glycoprotein synthesized by ...
Estrutura genética de populações naturais de Parides agavus (Lepidoptera; Papilionidae) da região central do Rio Grande do Sul, Brasil
(Universidade Federal de Santa Maria, 2007-03-21)
The population structure from the genetic and evolutive view-point tries to quantify the morphologic and quantitative variability existing among the individuals, their reproductive behavior, and gene flow patterns, and the ...
Desenvolvimento e validação de metodologia para análise de valdecoxibe. Avaliação de efeitos sobre parâmetros hematológicos
(Universidade Federal de Santa Maria, 2006-06-01)
Valdecoxib is a non-steroidal anti-inflammatory drug that represents a second-generation of cyclooxygenase-2 enzyme inhibitor and possesses anti-inflammatory, analgesic and antipyretic activities. In this work a reversed-phase ...
Desenvolvimento e validação de métodos cromatográficos para avaliação de interferon-alfa 2a em formulações farmacêuticas
(Universidade Federal de Santa Maria, 2009-03-17)
The interferon is a cytokine with antiviral, antiproliferative, and immunomodulatory
properties. It is a protein synthesized by cells in response to viral infection, producing successive
biochemistry alterations. The ...
Dietil-2-fenil-2-telurofenil vinilfosfonato: um composto orgânico de telúrio com atividade antioxidante in vitro e com baixa toxicidade in vivo em camundongos
(Universidade Federal de Santa Maria, 2007-02-14)
Despite the growing use of organotellurium compounds in chemical and biochemical fields, there is no great concern about their toxicity until now. Diethyl-2-phenyl-2-tellurophenyl vinylphospnonate is a β-organochalcogenyl ...