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ATP como modulador do sistema purinérgico e inflamação e status redox em pacientes com melanoma
(Universidade Federal de Santa Maria, 2019-09-16)
Melanoma is a type of skin cancer, formed in melanocytes, cells that produce the pigment melanin. The melanocytes of the epidermis are the most common places of melanoma’s origin; however, it can be also developed in ...
Efeitos do exercício resistido sobre a atividade das enzimas acetilcolinesterase e Na+/K+ ATPase e estresse oxidativo na hipertensão induzida por L-NAME
(Universidade Federal de Santa Maria, 2019-08-26)
Hypertension (HT) is a disease that affects billions of people around the world, being a
risk factor for numerous other cardiovascular diseases, and may even affect the brain
through poor blood distribution. In experimental ...
Efeitos da oxima butano-2,3-dionatiossemicarbazona frente ao dano testicular causado por cádmio em camundongos
(Universidade Federal de Santa Maria, 2014-03-06)
We investigated the action of butane-2,3-dione thiosemicarbazone oxime against the testicular damage caused by cadmium chloride (CdCl2) in mice swiss adult male. The animals received a single injection of CdCl2 at the dose ...
Influência da suplementação de diferentes ácidos graxos sobre o fotodano da pele induzido pela exposição de roedores à radiação ultravioleta
(Universidade Federal de Santa Maria, 2014-02-18)
Diet fatty acids (FA) are fundamental to the phospholipids structure and function of cell membranes, in which long chain polyunsaturated FA (PUFA) increase its fluidity, while the trans FA (TFA) to make it more rigid. Also, ...
Efeitos benéficos do extrato das cascas de noz pecã (Carya illinoensis) sobre parâmetros bioquímicos e comportamentais de camundongos expostos ao fumo passivo
(Universidade Federal de Santa Maria, 2011-01-28)
Smoking is the second major reason of death worldwide, amounting 5 millions
of deaths annually. The adverse effects of cigarette smoking are not limited to active
smokers, but also to passive smokers, which comprise one ...
Influência do exercício físico sobre parâmetros de comportamento e estresse oxidativo em modelo animal de discinesia tardia
(Universidade Federal de Santa Maria, 2008-03-07)
Regular practice of physical activity promotes beneficial effects to the body. However, excessive duration and intensity of exercise may surpass individual tolerance to
exercise, generating oxidative stress (OS). Studies ...
Estudo toxicológico comparativo referente ao haloperidol na sua forma livre e nanoencapsulada
(Universidade Federal de Santa Maria, 2015-08-14)
The association of haloperidol (HP) with polymeric nanocapsules causes a significant improve in therapeutic efficacy prolongs the drug time of action and reduces motor side effects in rats. However, in view of the HP ...
Disseleneto de m-trifluormetil-difenila modula as adaptações neurotóxicas e comportamentais induzidas pela retirada da morfina em camundongos
(Universidade Federal de Santa Maria, 2019-02-22)
Repeated use of morphine is controversial because it leads to the development of withdrawal syndrome, phenomenon involving a number of neuronal adaptations, which results on manifestations of physical signs and a state ...
Efeito da (+)-catequina sobre adiscinesia orofacial induzida por reserpina em camundongos e atividade damonoaminoxidase
(Universidade Federal de Santa Maria, 2018-03-20)
Tardive dyskinesia (TD) is a disabling and debilitating disorder due to the chronic use of antipsychotics that affects around 20% to 50% of patients. It is characterized by involuntary, repetitive and abnormal movements ...
Efeito toxicogenético do polimorfismo Ala16Val do gene MnSOD em leucócitos expostos in vitro ao metil mercúrio
(Universidade Federal de Santa Maria, 2012-03-19)
The environmental contamination by methyl mercury (MeHg) is a great health public problem in
some world regions like Amazonia. The MeHg toxic effects seem to be influenced by
environmental and genetic factors. However, ...