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Modelos de toxicidade da cisplatina em ratos adolescentes: papel protetor do disseleneto de difenila e do ebselen e avaliação da co-exposição ao estresse
(Universidade Federal de Santa Maria, 2022-04-19)
Cisplatin is a recommended chemotherapy drug for the treatment of pediatric and adult
neoplasms that, despite its wide use, is related to numerous serious adverse effects
such as neurotoxicity. In animal models using ...
Avaliação de marcadores bioquímicos, de estresse oxidativo e do efeito antioxidante da quercetina no hipotireoidismo
(Universidade Federal de Santa Maria, 2014-03-28)
Hypothyroidism is characterized by a disorder resulting from deficiency of
thyroid hormones and is related to lipid metabolism dysfunction and cardiovascular
diseases development risk. However, these changes in hypothyroidism ...
Participação do receptor de potencial transitório anquirina 1 e disfunção mitocondrial em um modelo de fibromialgia em camundongos
(Universidade Federal de Santa Maria, 2022-09-30)
Fibromyalgia is a painful condition associated with several comorbidities. Although the
mechanism underlying fibromyalgia remains unknown, monoamine depletion, reactive oxygen
species (ROS) overproduction, and mitochondrial ...
Efeitos do exercício físico sobre parâmetros de estresse oxidativo em ratos hipertensos
(Universidade Federal de Santa Maria, 2011-09-05)
Hypertension has been regarded as one of the most important factors associated with the
development of vascular disease and is closely linked to increased reactive oxygen species (ROS). In
contrast, exercise has been ...
Efeitos toxicológicos neonatal, transgeracional e crônico de piretroides em Caenorhabditis elegans
(Universidade Federal de Santa Maria, 2022-12-16)
The extensive use of domestic and agricultural insecticides to control domestic, crop and
even zootechnical pests has been growing in recent years. One of the main classes used
in the composition of insecticides are the ...
Influência do tipo de membrana de hemodiálise e da sua reutilização nos marcadores de estresse oxidativo
(Universidade Federal de Santa Maria, 2007-07-02)
The effects of the dialysis membranes, hemodialysis (HD) session, and dialyzer reuse on markers of oxidative stress were studied. Patients with end stage renal disease who have undergone regular HD treatment three times a ...
Avaliação de indicadores do estresse oxidativo e da atividade da enzima acetilcolinesterase sangüínea em pacientes com diagnóstico de acidente vascular cerebral isquêmico
(Universidade Federal de Santa Maria, 2006-09-29)
In ischemic stroke, damage to the brain is caused by a reduction or complete blockage of blood flow to parts of the brain, resulting in glucose and oxygen deficiency. It is a leading cause of mortality and disability ...
Parâmetros toxicológicos em jundiás (Rhamdia quelen) expostos ao cádmio
(Universidade Federal de Santa Maria, 2008-08-21)
The aquatic ecosystems may be constantly receiving metals from industrial discharges and agriculture generated by anthropogenic activities. Thus, the organisms in the aquatic environment may be the target of these contaminants. ...
Parâmetros toxicológicos em carpas (Cyprinus carpio) expostos a formulações comerciais de diferentes herbicidas em condições de lavoura de arroz e em laboratório
(Universidade Federal de Santa Maria, 2008-08-20)
Pesticides can affect toxicological parameters and cause oxidative stress in fish. In Brazil there are few studies linking pesticide toxicity with fish. For this reason,
two experiments were conducted to evaluate possible ...
Parâmetros toxicológicos em piavas (Leporinus obtusidens) e jundiás (Rhamdia quelen) após exposição a uma formulação comercial de glyphosate
(Universidade Federal de Santa Maria, 2008-02-15)
The commercial formulations of glyphosate herbicide have been widely used in agriculture and pisciculture for controlling plant weeds. Fish can be affected when drainage water reaches water courses, causing a disturbance ...