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Efeitos benéficos do ácido rosmarínico em modelos de atividade epileptiforme in vivo e in vitro induzidos por pilocarpina
(Universidade Federal de Santa Maria, 2021-12-17)
Epilepsy is a chronic neurological condition marked by the occurrence of epileptic seizures that cause enormous damage to the quality of life of affected patients. Thus, understanding the molecular bases responsible for ...
Avaliação dos efeitos do consumo de uma dieta rica em sacarose em Drosophila melanogaster: ênfase em alterações metabólicas e transcricionais
(Universidade Federal de Santa Maria, 2021-11-09)
The prevalence of diabetes mellitus (DM) has increased in the last decades, with 90% of cases been of type-2 diabetes (T2D), which is characterized by insulin resistance. In addition to hyperglycemia, T2D is strongly ...
Mecanismos neuroinflamatórios in vitro do alumínio em células microgliais: envolvimento da via de sinalização purinérgica
(Universidade Federal de Santa Maria, 2021-11-09)
Aluminum is a toxic metal to the nervous tissue and an etiological factor of neurodegenerative diseases, particularly Alzheimer's disease (AD). Furthermore, microglial cells and cellular signaling pathways, such as the ...
Efeito antiproliferativo, germinação de sementes e diversidade genética de Hesperozygis ringens (Benth.) Epling (Lamiaceae)
(Universidade Federal de Santa Maria, 2021-08-10)
Hesperozygis ringens is a species belonging to Lamiaceae. This shrub plant is
endemic to the Rio Grande do Sul and is located in restricted areas of a few
municipalities in the Rio Grande do Sul. Popularly known as ...
Avaliação do efeito do extrato aquoso de Ilex paraguariensis e cafeína sobre o metabolismo e a doença de Alzheimer em Caenorhabditis elegans
(Universidade Federal de Santa Maria, 2020-03-25)
Ilex paraguariensis is a plant widely consumed in South America, used to prepare a tea-like beverage, called mate, rich in caffeine and polyphenols, with multiple biological activities including antioxidant, anti-obesity ...
Interferência de Poa annua L. em Lolium multiflorum Lam. em função do ambiente de competição e do momento de estabelecimento
(Universidade Federal de Santa Maria, 2021-06-22)
The species Poa annua, of the poaceae family, has been shown to occur in pasture
environments in the state of Rio Grande do Sul. There is a great presence of this species as
a weed during the winter period, occupying an ...
Padrões de diversidade beta em comunidades de girinos (Amphibia: Anura) nos Campos Sulinos
(Universidade Federal de Santa Maria, 2020-02-27)
Studies investigating variation between communities are useful to understand the deterministic
and stochastic processes that shape the spatial and temporal communities’ distribution, mainly
using approaches that assess ...
Causas da distribuição de aves da Amazônia: uma questão da escala taxonômica
(Universidade Federal de Santa Maria, 2020-02-27)
One of the main questions in biogeography is the role of cladogenesis across barriers vs. ecological specialization on species distribution. In Amazonia, rivers have long been hypothesized to limit species dispersal and ...
Efeito genômico de bebidas ricas em cafeína e catequinas na modulação de marcadores oxidativos e inflamatórios associados a imunossenescência
(Universidade Federal de Santa Maria, 2021-12-10)
Introduction: Brazil has shown an accelerated aging process when compared to other countries in the world, a fact that directly impacts health and social care systems, as biological aging is associated with dysfunctions ...
O papel profilático do exercício físico sobre a modulação neurovascular e os efeitos da trombina no desenvolvimento de convulsões pós-traumáticas
(Universidade Federal de Santa Maria, 2021-08-30)
Traumatic brain injury (TBI) is considered a worldwide public health problem due to its high incidence and high public costs. Although the pathophysiology of TBI is multifaceted, the occurrence of coagulopathy is strongly ...