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Determinação do potencial antioxidante e anti-inflamatório tópico do extrato bruto das folhas de Casearia decandra Jacq.
(Universidade Federal de Santa Maria, 2017-03-09)
Casearia decandra Jacq is popularly known as "Guaçatonga" and is part of the Salicaceae family. Several therapeutic properties are attributed by the population, being used as diuretic, antiofidic, healing, anti-inflammatory ...
Desenvolvimento tecnológico de supositórios vaginais contendo nanopartículas poliméricas de tioconazol
(Universidade Federal de Santa Maria, 2015-08-14)
The development of nanostructured materials has provided better control of the release and targeting of active substances to the treatment site, minimizing adverse effects, in addition to contributing to increased therapeutic ...
Formulações nanoestruturadas contendo a associação coenzima Q10 e vitamina e acetato: desenvolvimento e avaliação de atividades biológicas
(Universidade Federal de Santa Maria, 2016-03-28)
Coenzyme Q10 is an endogenous synthesized molecule that presents antioxidant activity and
acts on cellular respiration process and ATP synthesis. Besides, it presents neuroprotective
effect, anti-inflammatory and ...
Extratos de folhas e sementes de Syzygium cumini (L.) Skeels protegem os linfócitos do dano oxidativo
(Universidade Federal de Santa Maria, 2017-01-20)
The use of medicinal plants for the purpose of treatment / prevention of diseases is common practice among the population, and has been associated with a lower risk for the development of several pathologies. Among these ...
Avaliação de diferentes marcadores de dano oxidativo, genotoxicidade e inflamação em trabalhadores expostos a solventes no município de Santa Maria, RS
(Universidade Federal de Santa Maria, 2015-03-13)
The organic solvents, also known as volatile organic compounds (VOCs) or volatile hydrocarbons, are widely used in a variety of industrial processes and consumer products. Gas station attendants (G.S.A.), as well as painters, ...
Atividade antimicobacteriana, antibiofilme e avaliação da toxicidade in vitro de complexos metálicos do sulfametoxazol
(Universidade Federal de Santa Maria, 2018-03-05)
Rapidly growing mycobacteria (RGM) are opportunistic microorganisms, found in the
environment, that can cause both local and disseminated infections. RGM can form structured
communities that adhere to solid ...
Avaliação dos efeitos toxicológicos do composto salicilaldeído-4-feniltiossemicarbazona (SPTS)
(Universidade Federal de Santa Maria, 2015-03-11)
The thiosemicarbazone compounds are of considerable scientific interest because of their important
biological and chemical properties, such as antitumor, antibacterial, antiviral, antiprotozoal, cytotoxic,
among others. ...
Desenvolvimento de nanopartículas poliméricas de Eudragit® RL 100 contendo tioconazol para tratamento de doença fúngica ocular
(Universidade Federal de Santa Maria, 2020-07-03)
The human eye, due to its unique structure and continuous exposure to the external environment, becomes susceptible to contamination by several pathogenic microorganisms, among which are fungi. In this way, the eye defence ...
Monitoramento da resposta molecular aos inibidores de tirosino-quinase em pacientes com leucemia mieloide crônica
(Universidade Federal de Santa Maria, 2019-02-28)
Chronic Myeloid Leukemia (CML) is associated with the chromosome Philadelphia. This abnormal
chromosome forms the chimeric BCR-ABL1 gene, which is responsible for producing a protein with
tyrosine kinase activity. Tyrosine ...
Perfil oxidativo do sangue de cordão umbilical de acordo com a duração do trabalho de parto de gestantes
(Universidade Federal de Santa Maria, 2019-01-22)
Oxidative stress is characterized by an imbalance between the production of free
radicals and the body's antioxidant capacity. It is known that labor is a process
characterized by an increase ...