Buscar
Itens para a visualização no momento 31-40 of 131
Efeitos da exposição isolada e combinada de larvas de anfíbio Boana curupi ao pesticida trichlorfon e à radiação ultravioleta
(Universidade Federal de Santa Maria, 2020-10-30)
The decline in global biodiversity affects mainly the amphibian group and several factors are identified as catalysts of this process. However, it is estimated that this decline is probably due to the interaction of multiple ...
Depressão induzida pela administração de dexametasona em camundongos: efeitos terapêuticos do disseleneto de p-clorodifenila
(Universidade Federal de Santa Maria, 2020-02-19)
Different animal models already reported that the administration of DEX can induce phenotypic behaviors of depression and anxiety, as well as brain molecular changes. However, most studies report on the effects of DEX from ...
Agressividade e ansiedade induzidas pelo estresse em peixe-zebra: envolvimento da monoamina oxidase, modulação redox e alterações neuroendócrinas
(Universidade Federal de Santa Maria, 2020-07-24)
Mental disorders are considered XXI century pandemics that cause various health diseases. About a third of people have problems related to mental health worldwide. Furthermore, several disorders are triggered by exacerbated ...
Efeito anti-inflamatório do ácido cafeico sobre o sistema purinérgico e colinérgico em ratos Diabéticos tipo 1
(Universidade Federal de Santa Maria, 2020-02-27)
Diabetes mellitus (DM) is a metabolic disorder, considered one of the biggest public health problems in the world. This disease is characterized by a state of chronic hyperglycemia that leads to metabolic disorders. Studies ...
Parâmetros moleculares e bioquímicos sobre a exposição per os aguda e crônica a xenobióticos eletrofílicos em insetos-modelos
(Universidade Federal de Santa Maria, 2020-08-13)
Continuous exposure to small doses of toxic substances elicit changes in the transcriptional profile and function of proteins before causing physical damage to organisms. Toxic effects can appear even after exposure stops. ...
Oleorresina de copaíba apresenta atividade antinociceptiva tópica em um modelo de queimadura de pele induzido por radiação UVB em camundongos
(Universidade Federal de Santa Maria, 2020-11-27)
Burn injuries are common worldwide, representing a major public health problem responsible for more than 180,000 deaths annually. These injuries can be caused by several factors, including ultraviolet (UV) radiation. ...
Parâmetros comportamentais e fisiológicos em peixes-zebra adultos expostos a cetamina
(Universidade Federal de Santa Maria, 2020-07-29)
Ketamine is an anesthetic widely used in human and veterinary clinic and also as a drug of abuse. It has dissociative anesthetic property that in subanesthetic doses induces analgesia. Although ketamine displays anxiolytic ...
Fibras musculares oxidativas e glicolíticas apresentam resposta inflamatória e alterações bioenergéticas peculiares após uma contusão musculoesquelética em ratos
(Universidade Federal de Santa Maria, 2021-02-19)
Muscle contusion represents a type of stress that disrupts cell homeostasis. Characterized by traumatic lesion, that impair the availability of oxygen (O2) in the tissue, promotes an increase in the production of reactive ...
Lacunas na evolução da via de reparo por excisão de nucleotídeos em eucariotos
(Universidade Federal de Santa Maria, 2020-10-21)
Nucleotide excision repair (NER) is the most versatile DNA repair pathway as it
removes different kinds of bulky lesions. Due to its essential role for genome integrity,
it appeared early in the evolution of species. ...
Avaliação da barata Nauphoeta cinerea como organismo modelo para o estudo de sepse
(Universidade Federal de Santa Maria, 2020-11-05)
Studies using model organisms, such as insects, are growing and have sought to investigate, in
a preliminary way, the mechanisms involved in the progression of infectious diseases,
examine potential pharmacological targets ...