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Efeitos do inseticida permetrina sobre o desenvolvimento de peixes-zebra
(Universidade Federal de Santa Maria, 2019-08-30)
Permethrin (PM) is a Type I synthetic pyrethroid (SP) widely used in crops and especially in domestic environments to control harmful insects. Pyrethroids are considered safe, with low mammalian toxicity. However, studies ...
Ação protetora da Carya illinoensis sobre a toxicidade induzida por ciclofosfamida em ratos
(Universidade Federal de Santa Maria, 2010-01-29)
Cyclophosphamide (CP) is an alkylating agent widely used in anticancer and immunosuppression therapy. Like other chemotherapies, this drug can induce damage in healthy tissues, generating multiple organ toxicity. The study ...
Adição do óleo essencial de Lippia alba (Mill) N. E. Brown na dieta do jundiá: análise do crescimento e da resposta antioxidante
(Universidade Federal de Santa Maria, 2013-02-06)
Fish become more susceptible to stress and, consequently, to the onset of disease with the intensification of rearing. In an attempt to minimize this problem, farmers use agrochemicals that, besides harming the environment, ...
Avaliação do potencial terapêutico do extrato aquoso de Peumus boldus (boldo) frente à toxicidade induzida por ferro e cobre em diferentes modelos experimentais
(Universidade Federal de Santa Maria, 2018-08-10)
The transition metals iron (Fe2+) and copper (Cu2+) are vital trace elements due to oxi-reducing
properties. However, the free Fe2+ and Cu2+ accumulation can lead to oxidative stress (OS), by catalisis
the Fenton reaction. ...
Efeitos do consumo de sacarose sobre parâmetros metabólicos, desenvolvimentais e antioxidantes em Drosophila melanogaster: papel das plantas Syzygium cumini e Bauhinia forficata
(Universidade Federal de Santa Maria, 2014-03-14)
The fruit fly, Drosophila melanogaster, has been considered a suitable model organism for investigation of developmental/metabolic dysfunctions and therapeutic strategies. In this work Drosophila melanogaster larvae were ...
Estudo comparativo dos efeitos tóxicos induzidos por metil e etilmercúrio em Saccharomyces cerevisiae
(Universidade Federal de Santa Maria, 2016-09-02)
Mercury is a highly toxic metal found in environment mostly due to anthropological and industrial processes. Methylmercury (MeHg) originates from the methylation of inorganic mercury in aquatic environment and accumulates ...
Dieta suplementada com disseleneto de difenila atenua as alterações bioquímicas e comportamentais no modelo de hipotireoidismo induzido por metimazol
(Universidade Federal de Santa Maria, 2012-12-14)
Hypothyroidism is a syndrome resulting from decreased production and secretion of triiothyronine (T3) and thyroxine (T4) hormones, frequently diagnosed in women. Clinical and experimental evidence support the association ...
ATP como modulador do sistema purinérgico e inflamação e status redox em pacientes com melanoma
(Universidade Federal de Santa Maria, 2019-09-16)
Melanoma is a type of skin cancer, formed in melanocytes, cells that produce the pigment melanin. The melanocytes of the epidermis are the most common places of melanoma’s origin; however, it can be also developed in ...
Efeitos do exercício resistido sobre a atividade das enzimas acetilcolinesterase e Na+/K+ ATPase e estresse oxidativo na hipertensão induzida por L-NAME
(Universidade Federal de Santa Maria, 2019-08-26)
Hypertension (HT) is a disease that affects billions of people around the world, being a
risk factor for numerous other cardiovascular diseases, and may even affect the brain
through poor blood distribution. In experimental ...
Efeitos da oxima butano-2,3-dionatiossemicarbazona frente ao dano testicular causado por cádmio em camundongos
(Universidade Federal de Santa Maria, 2014-03-06)
We investigated the action of butane-2,3-dione thiosemicarbazone oxime against the testicular damage caused by cadmium chloride (CdCl2) in mice swiss adult male. The animals received a single injection of CdCl2 at the dose ...