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Língua Brasileira de Sinais: o domínio dos contrastes mínimos
(Universidade Federal de Santa Maria, 2016-01-15)
The present doctoral thesis is an investigation of the perception of minimal contrasts in the Brazilian Sign Language - LIBRAS. To perform this investigation, it was proposed the preparation of an evaluation instrument, ...
Óleos essenciais de Myrcia sylvatica (G. Mey.) DC. e Curcuma longa L. como anestésicos para peixes: efeitos sobre as respostas fisiológicas
(Universidade Federal de Santa Maria, 2016-12-16)
The use of anesthetic substances is necessary to reduce stress and provide fish welfare during aquaculture
practices. The aim of this study was to investigate the use of Myrcia sylvativa (EOMS) and Curcuma longa
(EOCL) ...
Citocinas inflamatórias na urina como indicadores de dano renal em pacientes com diabetes mellitus tipo 2
(Universidade Federal de Santa Maria, 2016-12-20)
Diabetic kidney disease (DKD) is a highly prevalent microvascular complication in patients with diabetes mellitus (DM) and is the leading cause of end-stage renal disease in most countries. Until now, urinary albumin ...
Avaliação do dano ao DNA em pacientes com doença renal crônica submetidos à hemodiálise e sua associação com o metabolismo do ferro e estresse oxidativo
(Universidade Federal de Santa Maria, 2016-06-14)
Chronic kidney disease (CKD) is a condition in which the kidneys lose their ability to perform basic functions. Hemodialysis is the most commonly used alternative treatment for these patients, however, it exposes these ...
Efeito do desbalanço genético e farmacológico do metabolismo oxidativo em indicadores de fertilidade masculina
(Universidade Federal de Santa Maria, 2016-12-07)
Previous studies indicate that changes in oxidative metabolism may play a role in reproductive
success. Manganese-dependent superoxide dismutase enzyme (SOD2), a key in the oxidative
balance, presents a genetic variation ...
Efeito do extrato aquoso e de nanopartículas poliméricas contendo sementes de Syzygium cumini sobre complicações do diabetes mellitus in vitro e in vivo
(Universidade Federal de Santa Maria, 2016-12-13)
In the long term, diabetic patients have impaired cardiovascular system, as well as an imbalance in the immune system, which leads to increased susceptibility of these in contracting fungal infections. Diabetes mellitus ...
Avaliação fitoquímica, antioxidante e anti-inflamatória de Solanum corymbiflorum
(Universidade Federal de Santa Maria, 2017-02-20)
The plants have compounds that are related to different biological activities. Among these
compounds, stand out the phenolic compounds which are capable of eliminate free radicals,
and therefore, are involved in several ...
Efeitos de inibidores da enzima COX-2 sobre o desenvolvimento de crises convulsivas em camundongos
(Universidade Federal de Santa Maria, 2018-01-12)
Cyclooxygenase-2 (COX-2) inhibitors reduce the synthesis of prostaglandins (PGs) and play an important role in inflammation. In the last decades, research has been focused on the use of COX-2 inhibitors and the inflammatory ...
Influência de Harpagophytum procumbens sobre parâmetros comportamentais e moleculares em um modelo de discinesia orofacial em ratos
(Universidade Federal de Santa Maria, 2017-02-18)
Fluphenazine is a typical antipsychotic used for the treatment of schizophrenia. However, its chronic use has been related to the appearance of extrapyramidal side effects, such as tardive dyskinesia (TD). Studies suggest ...
Potencial antidepressivo do extrato aquoso de Ilex paraguariensis em roedores: envolvimento do sistema monoaminérgico
(Universidade Federal de Santa Maria, 2017-03-31)
Ilex paraguariensis is a plant largely consumed in South America as an infusion known as ―chimarrão‖ or ―mate‖, which shows effects related to its action in the central nervous system. However, little is known about its ...