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JM-20 como composto multialvo: avaliação do potencial antioxidante, inibidor de colinesterases e citotoxicidade
(Universidade Federal de Santa Maria, 2020-10-29)
Multi-target compounds have aroused the interest of many researchers. The main characteristic of these substances is the ability to act through different mechanisms of action, a relevant fact in cases of pathologies caused ...
Parâmetros moleculares e bioquímicos sobre a exposição per os aguda e crônica a xenobióticos eletrofílicos em insetos-modelos
(Universidade Federal de Santa Maria, 2020-08-13)
Continuous exposure to small doses of toxic substances elicit changes in the transcriptional profile and function of proteins before causing physical damage to organisms. Toxic effects can appear even after exposure stops. ...
Atividade radioprotetora, perfil toxicológico e efeito contra a toxicidade da ciclofosfamida do extrato de tucumã: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2020-08-04)
Cancer is a multifactorial disease characterized by loss of control of cell division. Nowadays, it is a serious health problem worldwide, leading to many deaths every year. Current treatments for cancer include radiation ...
Avaliação dos efeitos de curcumina e silimarina sobre a toxicidade induzida por micotoxinas in vitro e in vivo
(Universidade Federal de Santa Maria, 2020-10-08)
Mycotoxins are secondary metabolites produced by fungi and represent a worldwide concern
due to their global distribution and the harmful effects caused by their ingestion. This problem
presents itself in its most dramatic ...