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Influência do polimorfismo genético Val16Ala-SOD2 e da matriz química do guaraná no estado oxidativo-inflamatório in vitro do cloridrato de ziprasidona
(Universidade Federal de Santa Maria, 2019-03-12)
Antipsychotics (APs) are used to treat schizophrenia and other psychiatric disorders. Most of these
medications have adverse effects causing obesity and metabolic changes associated with oxidative
stress ...
Efeito da quercetina na sinalização purinérgica e no metabolismo oxidativo-inflamatório em modelo de artrite
(Universidade Federal de Santa Maria, 2018-12-17)
Rheumatoid arthritis (RA) is a chronic, autoimmune, inflammatory disease with predominant
involvement of the small joints, progressive destruction of cartilage and bone, and extra-
articular manifestations ...
Estudo longitudinal do perfil oxidativo em gestantes saudáveis e com complicações gestacionais
(Universidade Federal de Santa Maria, 2019-09-27)
During gestation, even though it is a physiological process, there is oxidative stress due to a
greater metabolic demand and an increase in tissue oxygen consumption, especially in the
placenta, in response to fetal ...
Estudo clínico, randomizado, controlado por placebo do efeito da suplementação de açaí em marcadores associados ao zumbido crônico
(Universidade Federal de Santa Maria, 2020-07-31)
Introduction: Chronic tinnitus is a subjective multifactorial symptom, in which different treatments are proposed for its management, antioxidants have been shown as an apparently promising perspective. Açaí extract, made ...
Status audiológico e marcadores de estresse oxidativo de adolescentes expostos a ruídos lazer
(Universidade Federal de Santa Maria, 2016-02-29)
The aim of the study was to determine the audiological status of adolescents exposed to recreational noise and investigate the possible association between these results and oxidative stress markers. 44 individuals were ...
Erva-mate (Ilex paraguariensis) e saúde: um estudo no metabolismo ósseo e sistema cardiovascular em mulheres pós-menopausa
(Universidade Federal de Santa Maria, 2018-07-05)
Menopause is an event characterized by the complete cessation of menstrual cycles as a
consequence of the important reduction of serum estrogen levels, which leads to increased
chronic diseases (osteoporosis, coronary ...
Efeito protetor da N-acetilcisteína sobre o estresse oxidativo causado pela administração crônica de aspartame em ratos
(Universidade Federal de Santa Maria, 2015-03-12)
This thesis evaluated the N-acetylcysteine effects (150 mg/kg, intraperitoneal) on the
biochemical and oxidative changes caused by the daily oral consumption of aspartame at 40
mg/kg for six weeks by rats. For this ...
Avaliação da Vanillosmopsis arborea Baker e (-)-α-bisabolol frente a parâmetros oxidativos e toxicológicos
(Universidade Federal de Santa Maria, 2017-08-18)
Vanillosmopsis arborea Baker belongs to the Asteraceae family and has a recognized economic value due to its anti-inflammatory properties, derived from sesquiterpene (-)-α-bisabolol (BISA), which is present in high ...
O efeito in vitro do extrato aquoso de erva mate (Ilex paraguariensis) na inflamação, estresse oxidativo e prevenção de sintomas parkinsonianos
(Universidade Federal de Santa Maria, 2018-05-03)
Parkinson's disease (PD) is a degenerative disease of the central nervous system, chronic and progressive. It is caused by an intense decrease in dopamine production. This disease is one of the main causes of neurological ...
Otoproteção da N-acetilcisteína e via de modulação da apoptose em células ciliadas de ratos tratados com cisplatina
(Universidade Federal de Santa Maria, 2015-03-10)
This paper aimed to investigate the apoptosis modulation pathway and the otoprotection mechanism of N-acetylcysteine (NAC) through the analysis of the glutathione peroxidase (GSH-Px) enzyme and the Bcl-2 protein expression ...