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Itens para a visualização no momento 231-240 of 497
Conservação de crustáceos límnicos: efeito da temperatura e pesticidas no metabolismo oxidativo de Aegla longirostri, in situ e ex-situ
(Universidade Federal de Santa Maria, 2021-08-31)
Freshwater ecosystems, especially low-order streams, are constantly threatened by the advance of agricultural activities that end up contaminating these places with pesticides and degrading the surrounding vegetation, which ...
Envolvimento do receptor de potencial transitório anquirina 1 e efeito farmacológico da diosmetina na queimadura de pele induzida pela radiação UVB em camundongos
(Universidade Federal de Santa Maria, 2021-05-11)
Excessive exposure to type B ultraviolet radiation (UVB) can lead to several changes to the skin resulting from the oxidative and inflammatory processes installed through the neuronal and non-neuronal receptors activation. ...
Fenótipos relacionados à dor em peixe-zebra: uma caracterização neurocomportamental utilizando o modelo de dor visceral induzida pelo ácido acético
(Universidade Federal de Santa Maria, 2021-08-26)
The zebrafish (Danio rerio) is a small freshwater teleost belonging to the Cyprinidae family, which has been studied in different scientific areas. This species has evolutionarily conserved genes and a relatively complex ...
Estudo da disfunção mitocondrial em modelos de doença de Parkinson in vitro e in vivo e perspectivas terapêuticas
(Universidade Federal de Santa Maria, 2021-10-01)
Parkinson disease (PD) is a neurodegenerative disease which symptoms are consequence of progressive neuron lost, especially dopaminergic neurons. Other feature related to PD is mitochondrial dysfunction which could target ...
Efeito neuroprotetor do exercício de natação e do disseleneto de m-trifluormetil difenila em um modelo de dieta hipercalórica em camundongos jovens
(Universidade Federal de Santa Maria, 2021-05-21)
The nutrition transition process has generated negative impacts on population health. The increasing consumption of foods and beverages with higher energy density and lower nutritional value promotes damage to the body, ...
Estudo do perfil oxidativo e avaliação de parâmetros enzimáticos em pacientes com câncer de próstata
(Universidade Federal de Santa Maria, 2012-12-19)
Prostate cancer is recognized as one of the most important medical problems in
the male population. Inherent or acquired alterations in cellular metabolism that occur
over the years may be involved in the process of ...
Estudo etnobotânico, microbiológico e perfil toxicológico in vitro e in vivo de Rhaphiodon echinus (Nees & Mart) Schauer
(Universidade Federal de Santa Maria, 2016-01-22)
Medicinal plants have long been used in traditional medicine for the treatment of various diseases, especially because they have low cost and lower toxicity compared to synthetic drugs. The pharmaco-toxicological interest ...
Estudo da adulteração com fármacos de suplementos alimentares para emagrecimento e avaliação in silico da interação fármaco-alimento entre sibutramina e grapefruit
(Universidade Federal de Santa Maria, 2016-08-22)
Dietary supplements are considered safe products for consumption because many of them are
from natural source. The consumption of these products has increased as an alternative in the
prevention and treatment of several ...
Efeitos do diclofenaco sobre marcadores inflamatórios e de estresse oxidativo em ratos submetidos a consecutivos sets exaustivos
(Universidade Federal de Santa Maria, 2021-07-07)
Physical exercise sessions represent some stress due to the fact that it alters body homeostasis. High oxygen consumption during exercise increases the production of reactive oxygen species (ROS) and pro-inflammatory ...
Efeito anti-inflamatório de formulações para aplicação tópica de ácido oleico e acetato de dexametasona em modelos experimentais de inflamação de pele
(Universidade Federal de Santa Maria, 2021-08-12)
The skin, as an interface space between the environment and the body, is constantly exposed to harmful effects from the external environment, which are capable of evoking an inflammatory response. Since the treatment for ...