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Ação antinociceptiva e anti-inflamatória da fração acetato de etila da casca da Scutia buxifolia Reiss em camundongos
(Universidade Federal de Santa Maria, 2016-02-12)
Pain and inflammation are physiological processes, which when persist can be harmful to health. The pain when improperly or left untreated can become chronic pain. Moreover, the inflammation can be involved in the pathogenesis ...
Desenvolvimento de nanocarreadores a base de piperina: influência do polímero e citotoxicidade in vitro – in vivo
(Universidade Federal de Santa Maria, 2016-12-16)
This study aimed the development of nanoemultions and polymeric nanocapsule suspensions containing
piperine, in order to study their considering photodegradation and citotoxicity. To quantify piperine at the
nanostructures, ...
Desenvolvimento de nanocápsulas poliméricas contendo Indol-3-Carbinol e avaliação biológica das formulações
(Universidade Federal de Santa Maria, 2016-08-08)
Indole-3carbinol (I3C) is a phytochemical that has several therapeutic properties. However, it is unstable
against acid and light conditions. In this sense, polymeric nanocapsules are interesting alternatives for
the ...
Avaliação in vitro da atividade de antimicrobianos na cavidade bucal sobre Candida glabrata sensíveis e resistentes ao fluconazol
(Universidade Federal de Santa Maria, 2016-03-21)
Oropharyngeal candidiasis is a challenging fungal disease in the clinical setting of immunocompromised patients, either by their morbidity or by its difficulties in treatment. Patients with AIDS, cancer, and transplanted ...
Desenvolvimento e validação de métodos cromatográficos para avaliação de teor/potência de insulina glargina
(Universidade Federal de Santa Maria, 2016-03-30)
hans, and is secreted into the bloodstream. It plays and important role in regulating the
metabolic activities of the body, particularly the homeostasis of the blood glucose. Insulin
glargine is a recombinant human insulin ...
Validação de métodos cromatográficos para avaliação de estreptoquinase e correlação com o bioensaio
(Universidade Federal de Santa Maria, 2016-03-30)
The streptokinase (STK) is a secreted and isolated molecule of β-hemolytic streptococci,
consists of 414 amino acids and clinically indicated as a thrombolytic agent for myocardial
infarction, deep vein thrombosis, ...
Glechon spathulata Benth. (Lamiaceae) compostos fenólicos e atividade biológica
(Universidade Federal de Santa Maria, 2016-08-31)
Glechon spathulata Bentham, belonging to the Lamiaceae family, is known as manjerona-do-campo, has its leaves used popularly as culinary flavoring, diaphoretic, stomachic in dyspepsia, antiseptic and expectorant in catarrhal ...
Vitis Vinifera L. cv Pinot Noir: bagaço e borra do vinho como potencial fonte de compostos bioativos
(Universidade Federal de Santa Maria, 2016-07-01)
Food and agricultural industries generate substantial quantities of phenolic-rich by-products
that could be valuable natural sources of antioxidants. The aim of this study was to identify
and quantify the phenolic compounds ...
Caracterização fenotípica e molecular da resistência a clindamicina em isolados clínicos de Staphylococcus aureus de um hospital terciário
(Universidade Federal de Santa Maria, 2016-08-11)
Staphylococcus aureus demonstrated over the time, the ability to develop resistance to the most antimicrobials. The mechanism of resistance to macrolides in S. aureus also reaches lincosamides and streptogramins B, featuring ...
Características genotípicas e fenotípicas de cepas de Escherichia coli isoladas de carne moída bovina in natura
(Universidade Federal de Santa Maria, 2016-01-15)
Escherichia coli is a bacterium that comprise the normal intestinal flora of warm-blooded
animals, responsible for a variety of diseases in humans, as bacteremia, urinary tract and
intestinal infections. Some become ...