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Avaliação das propriedades farmacológicas e farmacogenéticas do extrato e frações da planta Pavonia xanthogloea (Malvaceae)
(Universidade Federal de Santa Maria, 2014-01-31)
The Pampa Biome has a great biodiversity of plants, among them the Family Malvaceae. Despite the medicinal use of many of these plants, studies on the biological activity of these are still very scarce. This is the case ...
A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...
Influência de fatores farmacológicos e nutricionais na resposta oxidativa-inflamatória in vitro induzida pela olanzapina
(Universidade Federal de Santa Maria, 2019-03-13)
Introduction: Olanzapine (OLZ) is a second generation antipsychotic (ASG) used in the treatment of
schizophrenia, bipolar disorder and other neuropsychiatric conditions. The adverse effects of ASG
include ...
Propriedades neurofarmacológicas da Euterpe oleracea: estudo in vitro do potencial uso no tratamento de doenças psiquiátricas
(Universidade Federal de Santa Maria, 2017-01-26)
Introduction: Neuropsychiatric diseases, as bipolar disorder (BD), have a very complex pathophysiology. Several times the diagnostic and to choose a correct treatment are difficult. Currently, have been developed studies ...
Efeitos do álcool, percepção e comunicação de risco predatório em peixes zebra
(Universidade Federal de Santa Maria, 2017-12-13)
In prey-predator interactions, behavioral and hormonal changes can occur, besides as risk communication, already demonstrated in zebrafish through chemical cues. In addition, in several animal species, it is verified that ...
Mecanismos bioquímicos e moleculares envolvidos em efeitos comportamentais induzidos por reserpina em ratos e C. elegans com ênfase em parâmetros oxidativos e dopaminérgicos
(Universidade Federal de Santa Maria, 2015-01-16)
Animal models as reserpine are helpful to understand the pathophysiology of several diseases with involuntary movements, as Parkinson s disease (PD), and to search efficient treatments. The present study tested the effects ...
Efeito do extrato de Syzygium cumini e alterações provocadas pela síndrome metabólica sobre parâmetros bioquímicos e inflamatórios
(Universidade Federal de Santa Maria, 2013-12-04)
Metabolic syndrome (MetS) is a complex disorder represented by a set of cardiovascular risk factors, including endothelial dysfunction, oxidative stress and inflammation. Syzygium cumini has hypoglycemic, anti-inflammatory, ...
Papel da Na+, K+ - ATPase no modelo de epilepsia do lobo temporal em camundongos
(Universidade Federal de Santa Maria, 2015-03-16)
Epilepsy is a disease that affects about 1-2% of the general population. Considering the high number of patients with epilepsy who are refractory to currently available drugs, it is important to search for new anticonvulsant ...
Óleos essenciais como anestésicos para peixes: aspectos bioquímicos e moleculares
(Universidade Federal de Santa Maria, 2015-01-15)
The essential oil (EOs) extracted from plants Hesperozygis ringens and Lippia alba possess
anesthetic and sedative properties and is an alternative to traditional anesthetics used in
aquaculture for ease of handling ...
S. schenckii, S. luriei, S. brasiliensis e S. albicans: suscetibilidade a agentes antifúngicos combinados e caracterização de perfil enzimático
(Universidade Federal de Santa Maria, 2012-08-06)
Recently was proposed that Sporothrix schenckii is a complex encompassing six cryptic species, which calls for the reassessment of laboratory characteristics inherent susceptibility and virulence of this fungi complex. In ...