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Avaliação da atividade antinociceptiva do extrato e do alcaloide s-(+)-dicentrina extraído de frutos de Ocotea puberula (Lauraceae)
(Universidade Federal de Santa Maria, 2012-12-18)
Ocotea puberula (Lauraceae) is a brazilian native tree, known in the South regions as canela guaicá or canela amarela. Its phytochemical composition includes several alkaloids of aporphinic type, some of them with biological ...
Avaliação das propriedades farmacológicas e farmacogenéticas do extrato e frações da planta Pavonia xanthogloea (Malvaceae)
(Universidade Federal de Santa Maria, 2014-01-31)
The Pampa Biome has a great biodiversity of plants, among them the Family Malvaceae. Despite the medicinal use of many of these plants, studies on the biological activity of these are still very scarce. This is the case ...
A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...
Mecanismos bioquímicos e moleculares envolvidos em efeitos comportamentais induzidos por reserpina em ratos e C. elegans com ênfase em parâmetros oxidativos e dopaminérgicos
(Universidade Federal de Santa Maria, 2015-01-16)
Animal models as reserpine are helpful to understand the pathophysiology of several diseases with involuntary movements, as Parkinson s disease (PD), and to search efficient treatments. The present study tested the effects ...
Efeito do extrato de Syzygium cumini e alterações provocadas pela síndrome metabólica sobre parâmetros bioquímicos e inflamatórios
(Universidade Federal de Santa Maria, 2013-12-04)
Metabolic syndrome (MetS) is a complex disorder represented by a set of cardiovascular risk factors, including endothelial dysfunction, oxidative stress and inflammation. Syzygium cumini has hypoglycemic, anti-inflammatory, ...
Papel da Na+, K+ - ATPase no modelo de epilepsia do lobo temporal em camundongos
(Universidade Federal de Santa Maria, 2015-03-16)
Epilepsy is a disease that affects about 1-2% of the general population. Considering the high number of patients with epilepsy who are refractory to currently available drugs, it is important to search for new anticonvulsant ...
Óleos essenciais como anestésicos para peixes: aspectos bioquímicos e moleculares
(Universidade Federal de Santa Maria, 2015-01-15)
The essential oil (EOs) extracted from plants Hesperozygis ringens and Lippia alba possess
anesthetic and sedative properties and is an alternative to traditional anesthetics used in
aquaculture for ease of handling ...
S. schenckii, S. luriei, S. brasiliensis e S. albicans: suscetibilidade a agentes antifúngicos combinados e caracterização de perfil enzimático
(Universidade Federal de Santa Maria, 2012-08-06)
Recently was proposed that Sporothrix schenckii is a complex encompassing six cryptic species, which calls for the reassessment of laboratory characteristics inherent susceptibility and virulence of this fungi complex. In ...
O papel do íon ferro nas infecções por Pythium insidiosum
(Universidade Federal de Santa Maria, 2014-01-30)
The oomycete Pythium insidiosum, classified in the kingdom Straminipila, is the agent of pythiosis, a chronic disease that can be hard to treat and life-threatening. The predisposing factors in mammals are unknown, but the ...
Resíduos de risperidona no ambiente: efeitos persistentes e transgeracionais
(Universidade Federal de Santa Maria, 2018-12-13)
Contamination of aquatic environments by pharmaceutical components is a growing concern. Little is known about the consequences of exposure to these chemical agents, especially during the early stages of development. ...