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Atividade radioprotetora, perfil toxicológico e efeito contra a toxicidade da ciclofosfamida do extrato de tucumã: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2020-08-04)
Cancer is a multifactorial disease characterized by loss of control of cell division. Nowadays, it is a serious health problem worldwide, leading to many deaths every year. Current treatments for cancer include radiation ...
Avaliação dos efeitos de curcumina e silimarina sobre a toxicidade induzida por micotoxinas in vitro e in vivo
(Universidade Federal de Santa Maria, 2020-10-08)
Mycotoxins are secondary metabolites produced by fungi and represent a worldwide concern
due to their global distribution and the harmful effects caused by their ingestion. This problem
presents itself in its most dramatic ...
Estresse oxidativo e metabolismo ósseo em modelo roedor de síndrome dos ovários policísticos (SOP)
(Universidade Federal de Santa Maria, 2020-12-18)
Polycystic ovary syndrome (PCOS) is considered the commonest cause of endocrine infertility in women and affects around 8% of females at reproductive age. It is a complex disturbance, frequently associated with insulin ...
Efeito do antipsicótico haloperidol em Caenorhabditis elegans e do extrato bruto de Piper methysticum em camundongos sobre parâmetros comportamentais e bioquímicos
(Universidade Federal de Santa Maria, 2021-08-31)
Psychotic disorders, as schizophrenia and substance-induced psychoses (amphetamine, for example), are characterized by the appearance of delusions, hallucinations and other, and their symptoms are associated with hyperactivation ...
Farmacocinética de S-(+)-linalol em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2021-06-18)
S-(+)-linalool is found in essential oils of aromatic plants as Lippia alba. This phytochemical had its sedative/anesthetic activity elucidated in Rhamdia quelen, popularly known as silver catfish. Thus, S-(+)-linalool has ...
Suscetibilidade in vitro de Prototheca spp., isoladas de leite bovino, aos óleos essenciais, aos peptídeos e fármacos antimicrobianos
(Universidade Federal de Santa Maria, 2021-03-19)
Alchlorophilic algae of the genus Prototheca are disease-causing agents in humans and animals. The species Prototheca zopfii (genotype 2), with recent reclassification suggested for P. bovis, is cited by several authors ...
Fraturas ósseas em mulheres na pós-menopausa: um estudo de coorte em Santa Maria/RS
(Universidade Federal de Santa Maria, 2021-03-31)
Osteoporosis is characterized by low bone mass associated with abnormalities in bone microarchitecture, increasing the risk of fragility fractures. Although there are guidelines for the diagnosis and treatment of osteoporosis, ...
Eficácia, aceitabilidade e tolerabilidade do tratamento farmacológico do transtorno de estresse pós-traumático e dos antidepressivos na qualidade do sono de adultos com transtorno de estresse pós-traumático: revisões sistemáticas e metanálises em rede
(Universidade Federal de Santa Maria, 2021-08-25)
Pharmacological treatments for adults with post-traumatic stress disorder:
A network meta-analysis of comparative efficacy and acceptability.
Background: The purpose of this study was to compare efficacy and acceptability ...
Relação entre o sistema imune e o comportamento em zebrafish
(Universidade Federal de Santa Maria, 2020-03-06)
The interaction between immune system and behavior has already been observed in several studies using mammals as animal model. On the other hand, this relationship has not yet been clearly demonstrated in other animal ...
Efeitos do tipo ansiolítico e antiestresse da taurina em peixe-zebra (Danio rerio)
(Universidade Federal de Santa Maria, 2020-03-24)
Mental disorders are a major challenge to global health, considered 21st century pandemics. About a third of the world's disability is caused by mental health problems. Faced with this situation, World Health Organization ...