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Efeitos do consumo de ácidos graxos n-3, n-6 e trans sobre aspectos bioquímicos e moleculares em um modelo animal de mania
(Universidade Federal de Santa Maria, 2014-07-18)
Fatty acids (FA) are constituents of neuronal phospholipid membranes, where they are essential for the development and functioning of the brain. During the peak of neuronal growth, occurring during the last week of gestation ...
Atividade anestésica de óleos essenciais e constituintes isolados de plantas medicinais brasileiras em Rhamdia quelen
(Universidade Federal de Santa Maria, 2014-01-13)
The aim of this study was to obtain new fish anesthetic and sedative drugs from Brazilian
medicinal plants: Ocimum gratissimum (OG), Ocimum americanum (OA) e Hyptis mutabilis
(HM). Essential oils from these plants were ...
Avaliação das propriedades farmacológicas e farmacogenéticas do extrato e frações da planta Pavonia xanthogloea (Malvaceae)
(Universidade Federal de Santa Maria, 2014-01-31)
The Pampa Biome has a great biodiversity of plants, among them the Family Malvaceae. Despite the medicinal use of many of these plants, studies on the biological activity of these are still very scarce. This is the case ...
Efeito farmacogenômico in vitro do Astrocaryum aculeatum em células mononucleares do sangue periférico e de câncer de mama
(Universidade Federal de Santa Maria, 2014-01-21)
Breast cancer, due to their prevalence in our environment and global public health is a disease subject of numerous contemporary studies. Some of these studies suggest that certain genes related to cell cycle and apoptosis ...
Estudo experimental dos efeitos do canabidiol: possível estratégia para o tratamento da adição à anfetamina
(Universidade Federal de Santa Maria, 2022-02-04)
Amphetamine (AMPH) addiction is a chronic and relapsing disease caused by the compulsive drug seeking and
continued use despite harmful consequences. Currently, there is no effective and approved pharmacological
treatment ...
Influência da suplementação de diferentes ácidos graxos sobre o fotodano da pele induzido pela exposição de roedores à radiação ultravioleta
(Universidade Federal de Santa Maria, 2014-02-18)
Diet fatty acids (FA) are fundamental to the phospholipids structure and function of cell membranes, in which long chain polyunsaturated FA (PUFA) increase its fluidity, while the trans FA (TFA) to make it more rigid. Also, ...
Potencial terapêutico do extrato metanólico de Condalia buxifolia reissek no controle da dor aguda: estudo do mecanismo de ação
(Universidade Federal de Santa Maria, 2015-08-06)
The medicinal plant Condalia buxifolia has been traditionally used to treat inflammatory processes. The present study aimed to evaluate the phytochemical profile and the analgesic effect of the methanolic extract from the ...
Formação de produtos proteicos de oxidação avançada a partir da reação de fenton e colágeno: efeitos sobre processos inflamatórios em neutrófilos e células renais embrionárias
(Universidade Federal de Santa Maria, 2016-07-05)
The advanced oxidation protein products (AOPPs) are a new class of compounds identified as markers of oxidative damage to proteins. The physiology role of these products is not limited to assess the oxidative stress, and ...
Receptores EP1 E EP3 modulam as crises epilépticas induzidas por pentilenotetrazol e ácido caínico em camundongos
(Universidade Federal de Santa Maria, 2013-06-27)
Epilepsy is one of the most common neurologic disorders. It has been suggested that
seizures may be facilitaded by inflammation. PGE2 is one of the most important inflammatory
mediators, and facilitates pentylenetetrazol ...
Morfofisiologia de jundiás sedados ou anestesiados com MS222, óleo essencial de Aloysia triphylla e propofol
(Universidade Federal de Santa Maria, 2016-06-24)
One of the pillars for optimizing cultured fish handling is stress reduction, and sedatives and anesthetics are tools usually employed in order to reach such goal. However, these drugs may cause physiological changes that ...